Name : Human dipeptidyl peptidase IV\/CD26 in complex with a cyclohexalamine inhibitor
Revelation date : 22-May-2007
Family : DPP4N_Peptidase_S9
Gene_locus : human-DPP4
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Scapin, G., Biftu, T.
Ligand :
Title : Rational design of a novel, potent, and orally bioavailable cyclohexylamine DPP-4 inhibitor by application of molecular modeling and X-ray crystallography of sitagliptin - Biftu_2007_Bioorg.Med.Chem.Lett_17_3384 |
Author(s) : Biftu T , Scapin G , Singh S , Feng D , Becker JW , Eiermann G , He H , Lyons K , Patel S , Petrov A , Sinha-Roy R , Zhang B , Wu J , Zhang X , Doss GA , Thornberry NA , Weber AE |
Ref : Bioorganic & Medicinal Chemistry Lett , 17 :3384 , 2007 |
Abstract : Biftu_2007_Bioorg.Med.Chem.Lett_17_3384 |
ESTHER : Biftu_2007_Bioorg.Med.Chem.Lett_17_3384 |
PubMedSearch : Biftu_2007_Bioorg.Med.Chem.Lett_17_3384 |
PubMedID: 17433672 |
Gene_locus related to this paper: human-DPP4 |