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Structure Report for: 2OPH

Name|Human dipeptidyl peptidase IV in complex with an alpha amino acid inhibitor
Revelation date|08-May-2007
Family|DPP4N_Peptidase_S9: there are 829 genes in this family, 179 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Duffy, J.L., Kirk, B.A,, Wang, L., Eiermann, G.J., He, H., Leiting, B., Lyons, K.A., Patel, R.A., Patel, S.B. et. al, and Weber, A.E.
Ligand|Inhibitor: 4-aminocyclohexylalanine-derivative-25 Ligand in structure: Ligplot


    Title: 4-aminophenylalanine and 4-aminocyclohexylalanine derivatives as potent, selective, and orally bioavailable inhibitors of dipeptidyl peptidase IV
    Duffy JL, Kirk BA, Wang L, Eiermann GJ, He H, Leiting B, Lyons KA, Patel RA, Patel SB and Weber AE <4 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 17:2879, 2007 : PubMed


Representative scheme of DPP4N_Peptidase_S9 structure and an image from PDBsum server

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PDB-Sum2OPH Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP2OPH Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP2OPH Structural Classification Of Protein - SCOP server
PROTEOPEDIA2oph 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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