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Structure Report for: 2OGZ

Name|Crystal structure of DPP-IV complexed with Lilly aryl ketone inhibitor
Revelation date|06-Mar-2007
Family|DPP4N_Peptidase_S9: there are 829 genes in this family, 179 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Sheehan, S.M., Mest, H.J., Watson, B.M., Klimkowski, V.J., Timm, D.E., Cauvin, A., Parsons, S.H.
Ligand|Inhibitor: Lilly-aryl-ketone Ligand in structure: Ligplot


    Title: Discovery of non-covalent dipeptidyl peptidase IV inhibitors which induce a conformational change in the active site
    Sheehan SM, Mest HJ, Watson BM, Klimkowski VJ, Timm DE, Cauvin A, Parsons SH, Shi Q, Canada EJ and Weichert AG <15 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 17:1765, 2007 : PubMed


Representative scheme of DPP4N_Peptidase_S9 structure and an image from PDBsum server

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PDB-Sum2OGZ Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP2OGZ Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP2OGZ Structural Classification Of Protein - SCOP server
PROTEOPEDIA2ogz 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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