2OGZ
Name : Crystal structure of DPP-IV complexed with Lilly aryl ketone inhibitor
Revelation date : 06-Mar-2007
Family : DPP4N_Peptidase_S9
Gene_locus : human-DPP4
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Sheehan, S.M., Mest, H.J., Watson, B.M., Klimkowski, V.J., Timm, D.E., Cauvin, A., Parsons, S.H.
Ligand :
References (1)
| Title : Discovery of non-covalent dipeptidyl peptidase IV inhibitors which induce a conformational change in the active site - Sheehan_2007_Bioorg.Med.Chem.Lett_17_1765 |
| Author(s) : Sheehan SM , Mest HJ , Watson BM , Klimkowski VJ , Timm DE , Cauvin A , Parsons SH , Shi Q , Canada EJ , Wiley MR , Ruehter G , Evers B , Petersen S , Blaszczak LC , Pulley SR , Margolis BJ , Wishart GN , Renson B , Hankotius D , Mohr M , Zechel JC , Michael Kalbfleisch J , Dingess-Hammond EA , Boelke A , Weichert AG |
| Ref : Bioorganic & Medicinal Chemistry Lett , 17 :1765 , 2007 |
| Abstract : Sheehan_2007_Bioorg.Med.Chem.Lett_17_1765 |
| ESTHER : Sheehan_2007_Bioorg.Med.Chem.Lett_17_1765 |
| PubMedSearch : Sheehan_2007_Bioorg.Med.Chem.Lett_17_1765 |
| PubMedID: 17239592 |
| Gene_locus related to this paper: human-DPP4 |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
