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Structure Report for: 2HHA

Name|The structure of DPP4 in complex with an oxadiazole inhibitor
Revelation date|19-Sep-2006
Family|DPP4N_Peptidase_S9: there are 829 genes in this family, 179 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Scapin, G.
Ligand|Inhibitor: 3TP Ligand in structure: Ligplot


    Title: Discovery of potent, selective, and orally bioavailable oxadiazole-based dipeptidyl peptidase IV inhibitors
    Xu J, Wei L, Mathvink RJ, Edmondson SD, Eiermann GJ, He H, Leone JF, Leiting B, Lyons KA and Weber AE <7 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 16:5373, 2006 : PubMed


Representative scheme of DPP4N_Peptidase_S9 structure and an image from PDBsum server

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PDB-Sum2HHA Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP2HHA Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP2HHA Structural Classification Of Protein - SCOP server
PROTEOPEDIA2hha 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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