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Structure Report for: 2FJP

Name|Human dipeptidyl peptidase IV/CD26 in complex with an inhibitor
Revelation date|04-Jul-2006
Family|DPP4N_Peptidase_S9: there are 829 genes in this family, 179 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Edmondson, S.D., Mastracchio, A., Mathwink, R.J., He, J., Harper, B, Park, Y-J., Beconi, M., Di Salvo, J., Eirmann, G.J., He, H, Leiting, B., Leone, J.F., Levorse, D.A., Lyons, K., Patel, R.A., Patel, S.B., Petrov, A., Scapin, G., Shang, J., Roy, R.S., Sm
Ligand|Inhibitor: MK0626 Ligand in structure: Ligplot


    Title: (2S,3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-(4-[1,2,4]tr iazolo[1,5-a]-pyridin-6-ylphenyl)butanamide: a selective alpha-amino amide dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
    Edmondson SD, Mastracchio A, Mathvink RJ, He J, Harper B, Park YJ, Beconi M, Di Salvo J, Eiermann GJ and Weber AE <16 more author(s)>
    Ref: Journal of Medicinal Chemistry, 49:3614, 2006 : PubMed


Representative scheme of DPP4N_Peptidase_S9 structure and an image from PDBsum server

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PDB-Sum2FJP Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP2FJP Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP2FJP Structural Classification Of Protein - SCOP server
PROTEOPEDIA2fjp 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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