2CMF
Name : Torpedo californica acetylcholinesterase complexed with alkylene- linked bis-tacrine dimer (5 carbon linker)
Revelation date : 04-Sep-2006
Family : ACHE
Gene_locus : torca-ACHE
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Rydberg, E.H., Greenblatt, H.M., Wong, D.M., Pang, Y.P., Silman, I., Sussman, J.L
Ligand :
References (1)
| Title : Complexes of alkylene-linked tacrine dimers with Torpedo californica acetylcholinesterase: Binding of Bis5-tacrine produces a dramatic rearrangement in the active-site gorge - Rydberg_2006_J.Med.Chem_49_5491 |
| Author(s) : Rydberg EH , Brumshtein B , Greenblatt HM , Wong DM , Shaya D , Williams LD , Carlier PR , Pang YP , Silman I , Sussman JL |
| Ref : Journal of Medicinal Chemistry , 49 :5491 , 2006 |
| Abstract : Rydberg_2006_J.Med.Chem_49_5491 |
| ESTHER : Rydberg_2006_J.Med.Chem_49_5491 |
| PubMedSearch : Rydberg_2006_J.Med.Chem_49_5491 |
| PubMedID: 16942022 |
| Gene_locus related to this paper: torca-ACHE |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
