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Structure Report for: 2BUC

Name|Crystal structure of porcine dipeptidyl peptidase IV (CD26) in complex with a tetrahydroisoquinoline inhibitor
Revelation date|23-Jan-2006
Family|DPP4N_Peptidase_S9: there are 829 genes in this family, 179 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Nordhoff, S., Cerezo-Galvez, S., Feurer A., Hill, O., Matassa, V.G., Metz, G., Rummey, C., Thiemann, M., Edwards, P.J.
Ligand|Inhibitor: Tetrahydroisoquinoline-derivative Ligand in structure: Ligplot


    Title: The reversed binding of beta-phenethylamine inhibitors of DPP-IV: X-ray structures and properties of novel fragment and elaborated inhibitors
    Nordhoff S, Cerezo-Galvez S, Feurer A, Hill O, Matassa VG, Metz G, Rummey C, Thiemann M, Edwards PJ
    Ref: Bioorganic & Medicinal Chemistry Lett, 16:1744, 2006 : PubMed


Representative scheme of DPP4N_Peptidase_S9 structure and an image from PDBsum server

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PDB-Sum2BUC Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP2BUC Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP2BUC Structural Classification Of Protein - SCOP server
PROTEOPEDIA2buc 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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