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Structure Report for: 1ORW

Name|Crystal Structure of Porcine Dipeptidyl Peptidase IV (CD26) in Complex with a Peptidomimetic Inhibitor
Revelation date|06-May-2003
Family|DPP4N_Peptidase_S9: there are 829 genes in this family, 179 structure(s)
Gene_locus|pig-dpp4
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Ligand|Inhibitor: p-Iodo-Phe-Pyr-CN Ligand in structure: Ligplot


Reference

    Title: The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanism
    Engel M, Hoffmann T, Wagner L, Wermann M, Heiser U, Kiefersauer R, Huber R, Bode W, Demuth HU, Brandstetter H
    Ref: Proc Natl Acad Sci U S A, 100:5063, 2003 : PubMed

            



Representative scheme of DPP4N_Peptidase_S9 structure and an image from PDBsum server

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Databases

PDB-Sum1ORW Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP1ORW Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP1ORW Structural Classification Of Protein - SCOP server
PROTEOPEDIA1orw 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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