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Structure Report for: 7P1N

Name|Crystal structure of human acetylcholinesterase in complexe with (2R,3R,4S,5S,6R)-2-{4-[1-(4-{5-hydroxy-6-[(E)-(hydroxyimino)methyl]pyridin-2-yl}butyl)-1H-1,2,3-triazol-4-yl]butoxy}-6-(hydroxymethyl)oxane-3,4,5-triol oxime
Revelation date|08-Jun-2022
Family|ACHE: there are 541 genes in this family, 315 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Ophelie Da Silva.,Jose, Dias.,Florian, Nachon.
Ligand|Reactivator: 7P1N-4J1 Ligand in structure: Ligplot


    Title: A New Class of Bi- and Trifunctional Sugar Oximes as Antidotes against Organophosphorus Poisoning
    Da Silva O, Probst N, Landry C, Hanak AS, Warnault P, Coisne C, Calas AG, Gosselet F, Courageux C and Dias J <7 more author(s)>
    Ref: Journal of Medicinal Chemistry, :, 2022 : PubMed


Representative scheme of ACHE structure and an image from PDBsum server


PDB-Sum7P1N Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP7P1N Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP7P1N Structural Classification Of Protein - SCOP server
PROTEOPEDIA7p1n 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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