6TR7
Name : Structure of the human Wnt deacylase Notum in complex with N-[2-(5-fluoro-1H-indol-3-yl)ethyl]acetamide (6QCQ withdrawn)
Revelation date : 08-Jan-2020
Family : Pectinacetylesterase-Notum
Gene_locus : human-NOTUM
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Zhao, Y., Jones, E.Y.
Ligand :
References (2)
| Title : Structural Analysis and Development of Notum Fragment Screening Hits - Zhao_2022_ACS.Chem.Neurosci_13_2060 |
| Author(s) : Zhao Y , Mahy W , Willis NJ , Woodward HL , Steadman D , Bayle ED , Atkinson BN , Sipthorp J , Vecchia L , Ruza RR , Harlos K , Jeganathan F , Constantinou S , Costa A , Kjaer S , Bictash M , Salinas PC , Whiting P , Vincent JP , Fish PV , Jones EY |
| Ref : ACS Chem Neurosci , 13 :2060 , 2022 |
| Abstract : Zhao_2022_ACS.Chem.Neurosci_13_2060 |
| ESTHER : Zhao_2022_ACS.Chem.Neurosci_13_2060 |
| PubMedSearch : Zhao_2022_ACS.Chem.Neurosci_13_2060 |
| PubMedID: 35731924 |
| Gene_locus related to this paper: human-NOTUM |
| Title : Structural characterisation of melatonin as an inhibitor of the Wnt deacylase Notum - Zhao_2019_J.Pineal.Res__e12630 |
| Author(s) : Zhao Y , Ren J , Hillier J , Jones M , Lu W , Jones EY |
| Ref : J Pineal Res , :e12630 , 2019 |
| Abstract : Zhao_2019_J.Pineal.Res__e12630 |
| ESTHER : Zhao_2019_J.Pineal.Res__e12630 |
| PubMedSearch : Zhao_2019_J.Pineal.Res__e12630 |
| PubMedID: 31876313 |
| Gene_locus related to this paper: human-NOTUM |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
