Name : Crystal structure of human Lecithin:cholesterol acyltransferase (LCAT) in complex with isopropyl dodec-11-enylfluorophosphonate (IDFP) and a small molecule activator supersedes 6DTJ
Revelation date : 05-Dec-2018
Family : PC-sterol_acyltransferase
Gene_locus : human-LCAT
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Manthei, K.A., Yang, S., Baljinnyam, B., Chang, L., Glukhova, A., Yuan, W., Freeman, L.A., Shen, M., Maloney, D.J., Schwendeman, A., Remaley, A.T., Jadhav, A., Tesmer, J.J.G. There is a preprint available at Biorxiv<\/A>
Ligand :
Title : Molecular basis for activation of lecithin:cholesterol acyltransferase by a compound that increases HDL cholesterol - Manthei_2018_Elife_7_ |
Author(s) : Manthei KA , Yang SM , Baljinnyam B , Chang L , Glukhova A , Yuan W , Freeman LA , Maloney DJ , Schwendeman A , Remaley AT , Jadhav A , Tesmer JJ |
Ref : Elife , 7 : , 2018 |
Abstract : Manthei_2018_Elife_7_ |
ESTHER : Manthei_2018_Elife_7_ |
PubMedSearch : Manthei_2018_Elife_7_ |
PubMedID: 30479275 |
Gene_locus related to this paper: human-LCAT |