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Structure Report for: 6F25

Name|Crystal structure of human acetylcholinesterase in complex with C35
Revelation date|12-Dec-2018
Family|ACHE: there are 541 genes in this family, 315 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Dias, J., Nachon, F.
Ligand|Reactivator: C35-CVZ Ligand in structure: Ligplot


    Title: New evidence for dual binding site inhibitors of acetylcholinesterase as improved drugs for treatment of Alzheimer's disease
    Zueva IV, Dias J, Lushchekina SV, Semenov VE, Mukhamedyarov MA, Pashirova TN, Babaev VM, Nachon F, Petrova N and Petrov KA <4 more author(s)>
    Ref: Neuropharmacology, 155:131, 2019 : PubMed


Representative scheme of ACHE structure and an image from PDBsum server


PDB-Sum6F25 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP6F25 Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP6F25 Structural Classification Of Protein - SCOP server
PROTEOPEDIA6f25 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

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