Tree Display

AceDB Schema

XML Display


Structure Report for: 6EZG

Name|Torpedo californica acetylcholinesterase in complex with MR33112
Revelation date|21-Nov-2018
Family|ACHE: there are 543 genes in this family, 316 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Santoni, G., Lalut, J., Karila, D., Lecoutey, C., Davis, A., Nachon, F., Sillman, I., Sussman, J., Weik, M., Maurice, T., Dallemagne, P., Rochais, C.
Ligand|Inhibitor: Sigma1R-ACHE-6b Ligand in structure: Ligplot


    Title: Novel multitarget-directed ligands targeting acetylcholinesterase and sigma1 receptors as lead compounds for treatment of Alzheimer's disease: Synthesis, evaluation, and structural characterization of their complexes with acetylcholinesterase
    Lalut J, Santoni G, Karila D, Lecoutey C, Davis A, Nachon F, Silman I, Sussman JL, Weik M and Rochais C <2 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 162:234, 2019 : PubMed


Representative scheme of ACHE structure and an image from PDBsum server


PDB-Sum6EZG Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP6EZG Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP6EZG Structural Classification Of Protein - SCOP server
PROTEOPEDIA6ezg 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

Acknowledgements and disclaimer