Name : Structure of human monoacylglycerol lipase bound to PF-06795071 a covalent inhibitor
Revelation date : 14-Mar-2018
Family : Monoglyceridelipase_lysophospholip
Gene_locus : human-MGLL
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Pandit, J.
Ligand :
Title : Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation - McAllister_2018_J.Med.Chem_61_3008 |
Author(s) : McAllister LA , Butler CR , Mente S , O'Neil SV , Fonseca KR , Piro JR , Cianfrogna JA , Foley TL , Gilbert AM , Harris AR , Helal CJ , Johnson DS , Montgomery JI , Nason DM , Noell S , Pandit J , Rogers BN , Samad TA , Shaffer CL , da Silva RG , Uccello DP , Webb D , Brodney MA |
Ref : Journal of Medicinal Chemistry , 61 :3008 , 2018 |
Abstract : McAllister_2018_J.Med.Chem_61_3008 |
ESTHER : McAllister_2018_J.Med.Chem_61_3008 |
PubMedSearch : McAllister_2018_J.Med.Chem_61_3008 |
PubMedID: 29498843 |
Gene_locus related to this paper: human-MGLL |