4A5S
Name : Crystal Structure of human DDP4 in complex with a novel heterocyclic DPP4 inhibitor
Revelation date : 08-Feb-2012
Family : DPP4N_Peptidase_S9
Gene_locus : human-DPP4
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Ostermann, N., Kroemer, M., Zink, F., Gerhartz, B., Sutton, J.M., Clark, S.E., Dunsdon, S.J., Fenton, G., Fillmore, A., Harris, N.V., Higgs, C., Hurley, C.A., Krintel, S.L., MacKenzie, R.E., Duttaroy, A., Gangl, E., Maniara, W., Sedrani, R., Namoto, K., Sirockin, F., Trappe, J., Hassiepen, U., Baeschlin, D.K.
Ligand :
References (1)
| Title : Novel heterocyclic DPP-4 inhibitors for the treatment of type 2 diabetes. - Sutton_2012_Bioorg.Med.Chem.Lett_22_1464 |
| Author(s) : Sutton JM , Clark DE , Dunsdon SJ , Fenton G , Fillmore A , Harris NV , Higgs C , Hurley CA , Krintel SL , Mackenzie RE , Duttaroy A , Gangl E , Maniara W , Sedrani R , Namoto K , Ostermann N , Gerhartz B , Sirockin F , Trappe J , Hassiepen U , Baeschlin DK |
| Ref : Bioorganic & Medicinal Chemistry Lett , 22 :1464 , 2012 |
| Abstract : Sutton_2012_Bioorg.Med.Chem.Lett_22_1464 |
| ESTHER : Sutton_2012_Bioorg.Med.Chem.Lett_22_1464 |
| PubMedSearch : Sutton_2012_Bioorg.Med.Chem.Lett_22_1464 |
| PubMedID: 22177783 |
| Gene_locus related to this paper: human-DPP4 |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
