Name : Crystal Structure of Human Liver Carboxylesterase 1 (hCE1) in covalent complex with the nerve agent Cyclosarin (GF)
Revelation date : 19-Jan-2010
Family : Carb_B_Chordata
Gene_locus : human-CES1
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Hemmert, A.C., Otto, T.C., Weirdl, M., Potter, P.M., Cerasoli, D.M., Redinbo, M.R.
Ligand :
Title : Human carboxylesterase 1 stereoselectively binds the nerve agent cyclosarin and spontaneously hydrolyzes the nerve agent sarin - Hemmert_2010_Mol.Pharmacol_77_508 |
Author(s) : Hemmert AC , Otto TC , Wierdl M , Edwards CC , Fleming CD , MacDonald M , Cashman JR , Potter PM , Cerasoli DM , Redinbo MR |
Ref : Molecular Pharmacology , 77 :508 , 2010 |
Abstract : Hemmert_2010_Mol.Pharmacol_77_508 |
ESTHER : Hemmert_2010_Mol.Pharmacol_77_508 |
PubMedSearch : Hemmert_2010_Mol.Pharmacol_77_508 |
PubMedID: 20051531 |
Gene_locus related to this paper: human-CES1 |