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Structure Report for: 2Y2U

Name|Nonaged form of Mouse Acetylcholinesterase inhibited by VX-Update (superseeds 2JGH)
Revelation date|30-Nov-2011
Family|ACHE: there are 543 genes in this family, 316 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Akfur, C., Artursson, E., Ekstrom, F.
Ligand|Inhibitor: VX Ligand in structure: Ligplot


    Title: Crystal structures of acetylcholinesterase in complex with organophosphorus compounds suggest that the acyl pocket modulates the aging reaction by precluding the formation of the trigonal bipyramidal transition state
    Hornberg A, Tunemalm AK, Ekstrom F
    Ref: Biochemistry, 46:4815, 2007 : PubMed


Representative scheme of ACHE structure and an image from PDBsum server


PDB-Sum2Y2U Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP2Y2U Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP2Y2U Structural Classification Of Protein - SCOP server
PROTEOPEDIA2y2u 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

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