Name : Human Dipeptidyl peptidase IV in complex with 5-aminomethyl-6-(2,4-dichloro-phenyl)-2-(3,5-dimethoxy-phenyl)-pyrimidin-4-amine
Revelation date : 17-Dec-2004
Family : DPP4N_Peptidase_S9
Gene_locus : human-DPP4
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Hennig, M., Thoma, R., Stihle, M.
Ligand :
Title : Aminomethylpyrimidines as novel DPP-IV inhibitors: a 10(5)-fold activity increase by optimization of aromatic substituents - Peters_2004_Bioorg.Med.Chem.Lett_14_1491 |
Author(s) : Peters JU , Weber S , Kritter S , Weiss P , Wallier A , Boehringer M , Hennig M , Kuhn B , Loeffler BM |
Ref : Bioorganic & Medicinal Chemistry Lett , 14 :1491 , 2004 |
Abstract : Peters_2004_Bioorg.Med.Chem.Lett_14_1491 |
ESTHER : Peters_2004_Bioorg.Med.Chem.Lett_14_1491 |
PubMedSearch : Peters_2004_Bioorg.Med.Chem.Lett_14_1491 |
PubMedID: 15006388 |
Gene_locus related to this paper: human-DPP4 |