Two new lycodine-type alkaloids, huperzinineN-oxide (1) and 8,15-dihydrohuperzinine (2) as well asfive known compounds, huperzinine (3), huperzine B (4), huperzine D (5),N-demethylhuperzinine (6),and b-obscurine (7), were isolated from the club mossLycopodium casuarinoides. The structures of 1 and 2 were elucidated by spectroscopic methods and chemical transformation. The absolute configuration of 1was established by chemical correlation with 3, and that of 2 was determined by its CD spectrum.