Paper Report for: Whittaker_1981_Ann.Clin.Biochem_18_9
Reference
Title: A comparison of some methods of phenotyping the plasma cholinesterase variants using benzoylcholine as substrate Whittaker M, Britten JJ Ref: Annals of Clinical Biochemistry, 18:9, 1981 : PubMed
Five differential inhibitors of plasma cholinesterase have been compared using benzoylcholine as substrate. None of the inhibitors (dibucaine, NaF, NaBr, NaCl, or pancuronium dibutyryloxy bromide) could be used singly to resolve all the variants. Better resolution was obtained when two inhibitors were used in conjunction. Clear differentiation of all six genotypes was obtained only with the combined use of pancuronium dibutyryloxy bromide and sodium fluoride. The limitations of some of the parameters are discussed.
Whittaker M, Britten JJ (1981) A comparison of some methods of phenotyping the plasma cholinesterase variants using benzoylcholine as substrate Annals of Clinical Biochemistry18: 9-14
Whittaker M, Britten JJ (1981) Annals of Clinical Biochemistry18: 9-14