Paper Report for: Sancho_1997_Ecotoxicol.Environ.Saf_38_132
Reference
Title: Inhibition of gill Na+,K+-ATPase activity in the eel, Anguilla anguilla, by fenitrothion Sancho E, Ferrando MD, Andreu E Ref: Ecotoxicology & Environmental Safety, 38:132, 1997 : PubMed
European eels (Anguilla anguilla) were exposed to sublethal fenitrothion concentrations (0.02 and 0.04 mg/liter) in a continuous flow-through system for 4 days. Gill Mg2+- and Na+,K+-ATPase activities were evaluated after 2, 8, 12, 24, 32, 48, 56, 72, and 96 h of pesticide exposure. Results indicated that ATPase activity in gill tissue decreased as concentration of fenitrothion increased. Pesticide induced significant inhibitory effects on the Na+, K+-ATPase activity of A. anguilla, ranging from >56% inhibition at a sublethal concentration of 0.02 ppm to >73% inhibition at a sublethal concentration of 0.04 ppm. Eels were exposed to both fenitrothion concentrations for 96 h and then allowed a period of recovery in pesticide-free water. Samples were removed at 8, 12, 24, 48, 72, 96, 144, and 192 h and eel gill ATPase activity was evaluated. Following 1 week of recovery, the Na+,K+-ATPase activity for those animals previously exposed to 0.04 ppm fenitrothion was still different from that of the controls.
Sancho E, Ferrando MD, Andreu E (1997) Inhibition of gill Na+,K+-ATPase activity in the eel, Anguilla anguilla, by fenitrothion Ecotoxicology & Environmental Safety38: 132-6
Sancho E, Ferrando MD, Andreu E (1997) Ecotoxicology & Environmental Safety38: 132-6