Title: Arisugacins A and B, novel and selective acetylcholinesterase inhibitors from Penicillium sp. FO-4259. II. Structure elucidation Kuno F, Shiomi K, Otoguro K, Sunazuka T, Omura S Ref: Journal of Antibiotics, 49:748, 1996 : PubMed
The structures of new acetylcholinesterase inhibitors, arisugacins A and B, were elucidated by NMR study. Arisugacins have a (4aR,6aR,12aS,12bS)-4a,6,6a,12,12a, 12b-hexahydro-4a,12a-dihydroxy-4,4,6a,12b-tetramethyl-4H,11H -naphtho[2,1-b] pyrano[3,4-e]pyran-1,11(5H)-dione moiety in common and 3,4-dimethoxyphenyl or 4-methoxyphenyl residues are attached to C-9 of the moiety.
Kuno F, Shiomi K, Otoguro K, Sunazuka T, Omura S (1996) Arisugacins A and B, novel and selective acetylcholinesterase inhibitors from Penicillium sp. FO-4259. II. Structure elucidation Journal of Antibiotics49: 748-51
Kuno F, Shiomi K, Otoguro K, Sunazuka T, Omura S (1996) Journal of Antibiotics49: 748-51