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Paper Report for: Eckhardt_2007_J.Med.Chem_50_6450

Reference

Title: 8-(3-(R)-aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylme thyl)-3,7-dihydropurine-2,6-dione (BI 1356), a highly potent, selective, long-acting, and orally bioavailable DPP-4 inhibitor for the treatment of type 2 diabetes
Eckhardt M, Langkopf E, Mark M, Tadayyon M, Thomas L, Nar H, Pfrengle W, Guth B, Lotz R and Himmelsbach F <2 more author(s)>
Ref: Journal of Medicinal Chemistry, 50:6450, 2007 : PubMed

        



Related information

Gene_Locus| human-DPP4
Structure in RCSB-PDB | 2RGU
Structure in ESTHER | 2RGU
Inhibitor | Linagliptin,


Citations formats

Eckhardt M, Langkopf E, Mark M, Tadayyon M, Thomas L, Nar H, Pfrengle W, Guth B, Lotz R, Sieger P, Fuchs H, Himmelsbach F (2007)
8-(3-(R)-aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylme thyl)-3,7-dihydropurine-2,6-dione (BI 1356), a highly potent, selective, long-acting, and orally bioavailable DPP-4 inhibitor for the treatment of type 2 diabetes
Journal of Medicinal Chemistry 50: 6450-3

Eckhardt M, Langkopf E, Mark M, Tadayyon M, Thomas L, Nar H, Pfrengle W, Guth B, Lotz R, Sieger P, Fuchs H, Himmelsbach F (2007)
Journal of Medicinal Chemistry 50: 6450-3



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