Gene Locus : human-LPL
Mode of mutation : Natural mutant
Disease : Hyperlipoproteinemia TypeI
Summary :
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification :
Torpedo_number : No torpedo number
Kinetic Parameter : No kinetic parameter
News : No news
Comment : p.Y329X Tyr329Ter (Y302X Tyr302Ter in the mature protein which do not count signal peptide). in three homozygous patients rs118204081
Title : Spectrum of mutations of the LPL gene identified in Italy in patients with severe hypertriglyceridemia - Rabacchi_2015_Atherosclerosis_241_79 |
Author(s) : Rabacchi C , Pisciotta L , Cefalu AB , Noto D , Fresa R , Tarugi P , Averna M , Bertolini S , Calandra S |
Ref : Atherosclerosis , 241 :79 , 2015 |
Abstract : Rabacchi_2015_Atherosclerosis_241_79 |
ESTHER : Rabacchi_2015_Atherosclerosis_241_79 |
PubMedSearch : Rabacchi_2015_Atherosclerosis_241_79 |
PubMedID: 25966443 |
Gene_locus related to this paper: human-LPL |
Title : Pseudodominance of lipoprotein lipase (LPL) deficiency due to a nonsense mutation (Tyr302>Term) in exon 6 of LPL gene in an Italian family from Sardinia (LPL(Olbia)) - Bertolini_2000_Clin.Genet_57_140 |
Author(s) : Bertolini S , Simone ML , Pes GM , Ghisellini M , Rolleri M , Bellocchio A , Elicio N , Masturzo P , Calandra S |
Ref : Clin Genet , 57 :140 , 2000 |
Abstract : Bertolini_2000_Clin.Genet_57_140 |
ESTHER : Bertolini_2000_Clin.Genet_57_140 |
PubMedSearch : Bertolini_2000_Clin.Genet_57_140 |
PubMedID: 10735636 |
Gene_locus related to this paper: human-LPL |