W121E_drome-ACHE

General

Gene Locus : drome-ACHE

Mode of mutation : Site directed mutagenesis

Disease :

Summary : Back door hypothesis enlarge back channel Nachon_2008_Febs.J_275_2659

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : Back door hypothesis

Torpedo_number : 84

Kinetic Parameter : No kinetic parameter

News : APRIL-24-2008

Comment : Catalytic anionic site. Mutation W83E in mature protein. Numbering in Nachon_2008_Febs.J_275_2659 and Boublik et al. 2002 || p.Trp121Glu

References (1)

Title : Insights into substrate and product traffic in the Drosophila melanogaster acetylcholinesterase active site gorge by enlarging a back channel - Nachon_2008_FEBS.J_275_2659
Author(s) : Nachon F , Stojan J , Fournier D
Ref : Febs J , 275 :2659 , 2008
Abstract : Nachon_2008_FEBS.J_275_2659
ESTHER : Nachon_2008_FEBS.J_275_2659
PubMedSearch : Nachon_2008_FEBS.J_275_2659
PubMedID: 18422651