V288H_human-BCHE

General

Gene Locus : human-BCHE

Mode of mutation : Site directed mutagenesis

Disease :

Summary : Search for phosphotriesterase activity Phosphotriesterase activity Identical to WT Lockridge_1997_Biochemistry_36_786

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : Search for phosphotriesterase activity

Torpedo_number : 290

Kinetic Parameter : No kinetic parameter

News : No news

Comment : p.V288H Val288His (p.V316H Val316His in primary sequence with 28 amino-acids signal peptide) Phosphotriesterase activity Identical to WT

References (1)

Title : A single amino acid substitution, Gly117His, confers phosphotriesterase (organophosphorus acid anhydride hydrolase) activity on human butyrylcholinesterase - Lockridge_1997_Biochemistry_36_786
Author(s) : Lockridge O , Blong RM , Masson P , Froment MT , Millard CB , Broomfield CA
Ref : Biochemistry , 36 :786 , 1997
Abstract : Lockridge_1997_Biochemistry_36_786
ESTHER : Lockridge_1997_Biochemistry_36_786
PubMedSearch : Lockridge_1997_Biochemistry_36_786
PubMedID: 9020776