Gene Locus : human-CES1
Mode of mutation : Natural mutant
Disease :
Summary : Natural mutant decreased activity on enalapril clopidogrel and sacubitril Wang_2017_Drug.Metab.Dispos_45_1149
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : Natural mutation
Torpedo_number : 147
Kinetic Parameter : No kinetic parameter
News : No news
Comment : p.Gln169Pro Nucleotide change A614C rs143718310
| Title : A Comprehensive Functional Assessment of Carboxylesterase 1 Nonsynonymous Polymorphisms - Wang_2017_Drug.Metab.Dispos_45_1149 |
| Author(s) : Wang X , Rida N , Shi J , Wu AH , Bleske BE , Zhu HJ |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 45 :1149 , 2017 |
| Abstract : Wang_2017_Drug.Metab.Dispos_45_1149 |
| ESTHER : Wang_2017_Drug.Metab.Dispos_45_1149 |
| PubMedSearch : Wang_2017_Drug.Metab.Dispos_45_1149 |
| PubMedID: 28838926 |
| Gene_locus related to this paper: human-CES1 |