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Mutation Report for: L76S/H284Q/H287L_ratno-ACHE

Mode of mutation|Site directed mutagenesis
Amino Acid change|L76S/H284Q/H287L
Torpedo number|74//277//280//74,277,280
Comment|mutation with mouse numbering (L74S H277Q and H280L in torpedo numbering) this is the reverse of S74L, Q277H and L280H_eleel-ACHE which abolished inhibition by Elec-408
Kinetic parameters|none

    Title: The binding sites of inhibitory monoclonal antibodies on acetylcholinesterase. Identification of a novel regulatory site at the putative back door
    Simon S, Le Goff A, Frobert Y, Grassi J, Massoulie J
    Ref: Journal of Biological Chemistry, 274:27740, 1999 : PubMed


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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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