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Mutation Report for: K14Q/N354D_aphgo-cxest

K14Q/N354D_aphgo-cxest
Gene_Locus|aphgo-cxest
Mode of mutation|Natural mutant
Amino Acid change|K14Q/N354D
Torpedo number|19//376//19,376
Summary|
Comment|p.Lys14Gln/Asn354Asp The resistant strain (MRR) exhibited 80.6-fold resistance to malathion compared to the susceptible strain (MSS) in cotton aphids. The region K14 is not aligned to the Torpedo enzyme so the torpedo number for K14S is more 19-1
Kinetic parameters|none


References:
    Title: Carboxylesterase activity, cDNA sequence, and gene expression in malathion susceptible and resistant strains of the cotton aphid, Aphis gossypii
    Pan Y, Guo H, Gao X
    Ref: Comparative Biochemistry & Physiology B Biochem Mol Biol, 152:266, 2009 : PubMed

            




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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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