Gene Locus : human-BCHE
Mode of mutation : Site directed mutagenesis
Disease :
Summary : Search for phosphotriesterase activity Phosphotriesterase activity OP sensitive Millard_1995_Biochemistry_34_15925 Millard_1998_Biochemistry_37_237
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : Search for phosphotriesterase activity
Torpedo_number : 119
Kinetic Parameter : No kinetic parameter
News : No news
Comment : p.G117K Gly117Lys (p.G145K Gly145Lys in primary sequence with 28 amino-acids signal peptide) Phosphotriesterase activity OP sensitive
| Title : Protein engineering of a human enzyme that hydrolyzes V and G nerve agents: design, construction and characterization - Broomfield_1999_Chem.Biol.Interact_119-120_413 |
| Author(s) : Broomfield CA , Lockridge O , Millard CB |
| Ref : Chemico-Biological Interactions , 119-120 :413 , 1999 |
| Abstract : Broomfield_1999_Chem.Biol.Interact_119-120_413 |
| ESTHER : Broomfield_1999_Chem.Biol.Interact_119-120_413 |
| PubMedSearch : Broomfield_1999_Chem.Biol.Interact_119-120_413 |
| PubMedID: 10421478 |
| Title : Organophosphorus acid anhydride hydrolase activity in human butyrylcholinesterase: synergy results in a somanase - Millard_1998_Biochemistry_37_237 |
| Author(s) : Millard CB , Lockridge O , Broomfield CA |
| Ref : Biochemistry , 37 :237 , 1998 |
| Abstract : Millard_1998_Biochemistry_37_237 |
| ESTHER : Millard_1998_Biochemistry_37_237 |
| PubMedSearch : Millard_1998_Biochemistry_37_237 |
| PubMedID: 9425044 |
| Gene_locus related to this paper: human-BCHE |
| Title : Design and expression of organophosphorus acid anhydride hydrolase activity in human butyrylcholinesterase - Millard_1995_Biochemistry_34_15925 |
| Author(s) : Millard CB , Lockridge O , Broomfield CA |
| Ref : Biochemistry , 34 :15925 , 1995 |
| Abstract : Millard_1995_Biochemistry_34_15925 |
| ESTHER : Millard_1995_Biochemistry_34_15925 |
| PubMedSearch : Millard_1995_Biochemistry_34_15925 |
| PubMedID: 8519749 |