Gene Locus : human-CES1
Mode of mutation : Natural mutant
Disease :
Summary : Natural mutant decreased activity on enalapril clopidogrel and sacubitril Wang_2017_Drug.Metab.Dispos_45_1149
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : Natural mutation
Torpedo_number : 199
Kinetic Parameter : No kinetic parameter
News : No news
Comment : p.Glu220Gly Nucleotide change A767G rs200707504
| Title : A Comprehensive Functional Assessment of Carboxylesterase 1 Nonsynonymous Polymorphisms - Wang_2017_Drug.Metab.Dispos_45_1149 |
| Author(s) : Wang X , Rida N , Shi J , Wu AH , Bleske BE , Zhu HJ |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 45 :1149 , 2017 |
| Abstract : Wang_2017_Drug.Metab.Dispos_45_1149 |
| ESTHER : Wang_2017_Drug.Metab.Dispos_45_1149 |
| PubMedSearch : Wang_2017_Drug.Metab.Dispos_45_1149 |
| PubMedID: 28838926 |
| Gene_locus related to this paper: human-CES1 |
| Title : Investigating the impact of missense mutations in hCES1 by in silico structure-based approaches - Nzabonimpa_2016_Drug.Metab.Pers.Ther__ |
| Author(s) : Nzabonimpa GS , Rasmussen HB , Brunak S , Taboureau O |
| Ref : Drug Metab Pers Ther , : , 2016 |
| Abstract : Nzabonimpa_2016_Drug.Metab.Pers.Ther__ |
| ESTHER : Nzabonimpa_2016_Drug.Metab.Pers.Ther__ |
| PubMedSearch : Nzabonimpa_2016_Drug.Metab.Pers.Ther__ |
| PubMedID: 26900165 |
| Gene_locus related to this paper: human-CES1 |