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Mutation Report for: E197C_human-BCHE

E197C_human-BCHE
Gene_Locus|human-BCHE
Mode of mutation|Site directed mutagenesis
Amino Acid change|E197C
Torpedo number|199
Summary|
Comment|p.E197C Glu197Cys (p.E225C Glu225Cys in primary sequence with 28 amino-acids signal peptide) OP-resistance
Kinetic parameters|none


References:
    Title: Identification of Human Butyrylcholinesterase Organophosphate-Resistant Variants through a Novel Mammalian Enzyme Functional Screen
    Zhang J, Chen S, Ralph EC, Dwyer MA, Cashman JR
    Ref: Journal of Pharmacology & Experimental Therapeutics, 343:673, 2012 : PubMed

            




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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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