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Mutation Report for: C580S_human-ACHE

Mode of mutation|Site directed mutagenesis
Amino Acid change|C580S
Torpedo number|572
Comment|p.C580S Cys580Ser (p.C611S Cys611Ser in primary sequence with 31 amino-acids signal peptide) Subunit assembly;Dimerization deficient mutant
Kinetic parameters|none

    Title: Recombinant human acetylcholinesterase expressed in Escherichia coli: refolding, purification and characterization
    Fischer M, Ittah A, Gorecki M, Werber MM
    Ref: Biotechnol Appl Biochem, 21:295, 1995 : PubMed


    Title: Expression and reconstitution of biologically active human acetylcholinesterase from Escherichia coli
    Fischer M, Ittah A, Liefer I, Gorecki M
    Ref: Cellular Molecular Neurobiology, 13:25, 1993 : PubMed


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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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