Gene Locus : tetur-ACHE
Mode of mutation : Natural mutant
Disease :
Summary : OP-resistance Insecticide resistance Khajehali_2010_Pest.Manag.Sci_66_220 || OP-resistance Insecticide resistance Kwon_2010_Pestic.Biochem.Physiol_96_36 || OP-resistance Insecticide resistance, amplified allele Kwon_2010_Insect.Mol.Biol_19_195 || OP-resistance Insecticide resistance, amplified allele Kwon_2012_Insect.Biochem.Mol.Biol_42_212
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : OP-resistance
Torpedo_number : 280
Kinetic Parameter : No kinetic parameter
News : NOVEMBER-21-2009
Comment : Khajehali et al. found this modification in all three OP strains but not all clones. This mutation does not seem to be responsible for the modification of the biochemical properties of AChE1. This residue is not conserved among species and both resistant and susceptible strains of T. urticae from Japan have a T at position 280. Kwon et al. present evidences that A280T reduce OP sensitivity of AChE and contribute to resistance. The amino acid substitution was modified accordingly in the database || AChE gene duplication results in the proportional overexpression which is necessary for the reduced catalytic activity caused by mutations || p.Ala280Thr
| Title : Identification and characterization of striking multiple-insecticide resistance in a Tetranychus urticae field population from Greece - Papapostolou_2021_Pest.Manag.Sci_77_666 |
| Author(s) : Papapostolou KM , Riga M , Charamis J , Skoufa E , Souchlas V , Ilias A , Dermauw W , Ioannidis P , Van Leeuwen T , Vontas J |
| Ref : Pest Manag Sci , 77 :666 , 2021 |
| Abstract : Papapostolou_2021_Pest.Manag.Sci_77_666 |
| ESTHER : Papapostolou_2021_Pest.Manag.Sci_77_666 |
| PubMedSearch : Papapostolou_2021_Pest.Manag.Sci_77_666 |
| PubMedID: 33051974 |
| Gene_locus related to this paper: tetur-ACHE |
| Title : Geographical distribution and origin of acetylcholinesterase mutations conferring acaricide resistance in Tetranychus urticae populations from Turkey - Inak_2021_Exp.Appl.Acarol__ |
| Author(s) : Inak E |
| Ref : Exp Appl Acarol , : , 2021 |
| Abstract : Inak_2021_Exp.Appl.Acarol__ |
| ESTHER : Inak_2021_Exp.Appl.Acarol__ |
| PubMedSearch : Inak_2021_Exp.Appl.Acarol__ |
| PubMedID: 34731389 |
| Title : Global distribution and origin of target site insecticide resistance mutations in Tetranychus urticae - Ilias_2014_Insect.Biochem.Mol.Biol_48_17 |
| Author(s) : Ilias A , Vontas J , Tsagkarakou A |
| Ref : Insect Biochemistry & Molecular Biology , 48 :17 , 2014 |
| Abstract : Ilias_2014_Insect.Biochem.Mol.Biol_48_17 |
| ESTHER : Ilias_2014_Insect.Biochem.Mol.Biol_48_17 |
| PubMedSearch : Ilias_2014_Insect.Biochem.Mol.Biol_48_17 |
| PubMedID: 24602758 |
| Gene_locus related to this paper: tetur-ACHE |
| Title : The overexpression of acetylcholinesterase compensates for the reduced catalytic activity caused by resistance-conferring mutations in Tetranychus urticae - Kwon_2012_Insect.Biochem.Mol.Biol_42_212 |
| Author(s) : Kwon DH , Choi JY , Je YH , Lee SH |
| Ref : Insect Biochemistry & Molecular Biology , 42 :212 , 2012 |
| Abstract : Kwon_2012_Insect.Biochem.Mol.Biol_42_212 |
| ESTHER : Kwon_2012_Insect.Biochem.Mol.Biol_42_212 |
| PubMedSearch : Kwon_2012_Insect.Biochem.Mol.Biol_42_212 |
| PubMedID: 22198354 |
| Gene_locus related to this paper: tetur-ACHE |
| Title : Acetylcholinesterase point mutations putatively associated with monocrotophos resistance in the two-spotted spider mite - Kwon_2010_Pestic.Biochem.Physiol_96_36 |
| Author(s) : Kwon DH , Im JS , Ahn JJ , Lee J-H , Clark JM , Lee SH |
| Ref : Pesticide Biochemistry and Physiology , 96 :36 , 2010 |
| Abstract : Kwon_2010_Pestic.Biochem.Physiol_96_36 |
| ESTHER : Kwon_2010_Pestic.Biochem.Physiol_96_36 |
| PubMedSearch : Kwon_2010_Pestic.Biochem.Physiol_96_36 |
| PubMedID: |
| Gene_locus related to this paper: tetur-ACHE |
| Title : Acetylcholinesterase point mutations in European strains of Tetranychus urticae (Acari: Tetranychidae) resistant to organophosphates - Khajehali_2010_Pest.Manag.Sci_66_220 |
| Author(s) : Khajehali J , Van Leeuwen T , Grispou M , Morou E , Alout H , Weill M , Tirry L , Vontas J , Tsagkarakou A |
| Ref : Pest Manag Sci , 66 :220 , 2010 |
| Abstract : Khajehali_2010_Pest.Manag.Sci_66_220 |
| ESTHER : Khajehali_2010_Pest.Manag.Sci_66_220 |
| PubMedSearch : Khajehali_2010_Pest.Manag.Sci_66_220 |
| PubMedID: 19894225 |
| Gene_locus related to this paper: tetur-ACHE |
| Title : Extensive gene duplication of acetylcholinesterase associated with organophosphate resistance in the two-spotted spider mite - Kwon_2010_Insect.Mol.Biol_19_195 |
| Author(s) : Kwon DH , Clark JM , Lee SH |
| Ref : Insect Molecular Biology , 19 :195 , 2010 |
| Abstract : Kwon_2010_Insect.Mol.Biol_19_195 |
| ESTHER : Kwon_2010_Insect.Mol.Biol_19_195 |
| PubMedSearch : Kwon_2010_Insect.Mol.Biol_19_195 |
| PubMedID: 20002213 |
| Gene_locus related to this paper: tetur-ACHE |