A158V_human-CES1

General

Gene Locus : human-CES1

Mode of mutation : Natural mutant

Disease :

Summary : Natural mutant\;decreased activity on enalapril\;Wang_2017_Drug.Metab.Dispos_45_1149

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : Natural mutation

Torpedo_number : 136

Kinetic Parameter : No kinetic parameter

News : No news

Comment : p.Ala158Val Nucleotide change C581T rs202121317

References (1)

Title : A Comprehensive Functional Assessment of Carboxylesterase 1 Nonsynonymous Polymorphisms - Wang_2017_Drug.Metab.Dispos_45_1149
Author(s) : Wang X , Rida N , Shi J , Wu AH , Bleske BE , Zhu HJ
Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 45 :1149 , 2017
Abstract : Wang_2017_Drug.Metab.Dispos_45_1149
ESTHER : Wang_2017_Drug.Metab.Dispos_45_1149
PubMedSearch : Wang_2017_Drug.Metab.Dispos_45_1149
PubMedID: 28838926
Gene_locus related to this paper: human-CES1