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Kinetic parameters for mutation Y72A_human-ACHE

Substrate

MoleculeKmKcatExp. conditionsReference
Acetylthiocholine 130 uM 380000/min 50mM Na phosphate pH8 Barak_1994_J.Biol.Chem_269_6296

Inhibitor

MoleculeKiKsiIc50Exp. conditionsSubstrateReference
BW284C51 22 nM - - 50mM Na phosphate pH8 Acetylthiocholine Barak_1994_J.Biol.Chem_269_6296
Decamethonium 13 uM - - 50mM Na phosphate pH8 Acetylthiocholine Barak_1994_J.Biol.Chem_269_6296
Edrophonium 0.3 uM - - 50mM Na phosphate pH8 Acetylthiocholine Barak_1994_J.Biol.Chem_269_6296
Hexamethonium 0.35 mM - - 50mM Na phosphate pH8 Acetylthiocholine Barak_1994_J.Biol.Chem_269_6296
Propidium 5.3 uM - - 50mM Na phosphate pH8 Acetylthiocholine Barak_1994_J.Biol.Chem_269_6296
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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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