Inhibitor

Bibliography

Biblio print

Tree Display

AceDB Schema

XML Display

Feedback

Inhibitor Report for: sec-Pentylsarin

General
Type Chemical Warfare Agent, Organophosphate, Nerve Agent G-series, Derivative of Sarin
Chemical_Nomenclature 1-[fluoro(methyl)phosphoryl]oxy-2-methylbutane
Canonical SMILES CCC(C)COP(=O)(C)F
InChI InChI=1S/C6H14FO2P/c1-4-6(2)5-9-10(3,7)8/h6H,4-5H2,1-3H3
InChIKey DMFJLEAYMVMZDZ-UHFFFAOYSA-N
Other name(s) 2-Methyl-1-butyl methylphosphonofluoridate ; AC1LC0IN ; CTK6C8846 ; 2-methylbutyl methylphosphonofluoridate
________________________________________________________________________________________________
MW|168.14
Formula|C6H14FO2P
CAS_number|
PubChem|567432
UniChem|DMFJLEAYMVMZDZ-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | sec-Pentylsarin ligand of proteins in family: ACHE, BCHE

References:
Search PubMed for references concerning: sec-Pentylsarin
    Title: Efficacy of the rePON1 mutant IIG1 to prevent cyclosarin toxicity in vivo and to detoxify structurally different nerve agents in vitro
    Worek F, Seeger T, Goldsmith M, Ashani Y, Leader H, Sussman JL, Tawfik DS, Thiermann H, Wille T
    Ref: Archives of Toxicology, 88:1257, 2014 : PubMed

            

    Title: Interaction of pentylsarin analogues with human acetylcholinesterase: a kinetic study
    Worek F, Herkert NM, Koller M, Aurbek N, Thiermann H
    Ref: Toxicol Lett, 187:119, 2009 : PubMed