alkyne-PEG-FP
Non specific serine hydrolases (SH) probe. Contains a clickable alkyne tag, it is possible to conjugate with a reporter group (i.e. biotin azide or rhodamine azide) using click chemistry
General
Type : Organophosphate,ABPP-Probe,Fluorescent Probe,Alkyne
Chemical_Nomenclature : 5-[2-[2-[2-[2-[ethoxy(fluoro)phosphoryl]ethoxy]ethoxy]ethoxy]ethoxy]pent-1-yne
Canonical SMILES : CCOP(=O)(CCOCCOCCOCCOCCCC#C)F
InChI : InChI=1S\/C15H28FO6P\/c1-3-5-6-7-18-8-9-19-10-11-20-12-13-21-14-15-23(16,17)22-4-2\/h1H,4-15H2,2H3
InChIKey : UVPAJAAPPUVBDC-UHFFFAOYSA-N
Other name(s) : SCHEMBL20832336
MW : 354.35
Formula : C15H28FO6P
CAS_number :
PubChem : 138484657
UniChem : UVPAJAAPPUVBDC-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
Families :
Stucture :
Protein : myctu-Rv2284 || myctu-Rv2970c || myctu-ym24 || myctu-rv0183 || myctu-RV1683
References (2)
| Title : Small-Molecule Probes Reveal Esterases with Persistent Activity in Dormant and Reactivating Mycobacterium tuberculosis - Tallman_2016_ACS.Infect.Dis_2_936 |
| Author(s) : Tallman KR , Levine SR , Beatty KE |
| Ref : ACS Infect Dis , 2 :936 , 2016 |
| Abstract : Tallman_2016_ACS.Infect.Dis_2_936 |
| ESTHER : Tallman_2016_ACS.Infect.Dis_2_936 |
| PubMedSearch : Tallman_2016_ACS.Infect.Dis_2_936 |
| PubMedID: 27690385 |
| Gene_locus related to this paper: myctu-rv0183 , myctu-Rv1399c , myctu-RV1683 , myctu-Rv2284 , myctu-Rv2970c , myctu-ym24 |
| Title : Multiplexed activity-based protein profiling of the human pathogen Aspergillus fumigatus reveals large functional changes upon exposure to human serum - Wiedner_2012_J.Biol.Chem_287_33447 |
| Author(s) : Wiedner SD , Burnum KE , Pederson LM , Anderson LN , Fortuin S , Chauvigne-Hines LM , Shukla AK , Ansong C , Panisko EA , Smith RD , Wright AT |
| Ref : Journal of Biological Chemistry , 287 :33447 , 2012 |
| Abstract : Wiedner_2012_J.Biol.Chem_287_33447 |
| ESTHER : Wiedner_2012_J.Biol.Chem_287_33447 |
| PubMedSearch : Wiedner_2012_J.Biol.Chem_287_33447 |
| PubMedID: 22865858 |