ZK8
covalent inhibitor used to transform an esterase into an enantioselective catecholase through bioconjugation of this versatile metal-chelating inhibitor
General
Type : Organophosphate,Pyridine,Metal ion chelator
Chemical_Nomenclature : hexyl-[2-(3-oxidanylpyridin-2-yl)pyridin-3-yl]oxy-phosphinic acid
Canonical SMILES : CCCCCCP(=O)(O)OC1=C(N=CC=C1)C2=C(C=CC=N2)O
InChI : InChI=1S\/C16H21N2O4P\/c1-2-3-4-5-12-23(20,21)22-14-9-7-11-18-16(14)15-13(19)8-6-10-17-15\/h6-11,19H,2-5,12H2,1H3,(H,20,21)
InChIKey : QYCWYIQRYAMGGW-UHFFFAOYSA-N
Other name(s) :
MW : 336.32
Formula : C16H21N2O4P
CAS_number :
PubChem : 168355673
UniChem : QYCWYIQRYAMGGW-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
Families : ZK8 ligand of proteins in family: Hormone-sensitive_lipase_like
Stucture :
Protein : 9zzzz-a0a2k8jn75
References (1)
| Title : Transforming an esterase into an enantioselective catecholase through bioconjugation of a versatile metal-chelating inhibitor - Fernandez-Lopez_2023_Chem.Commun.(Camb)__ |
| Author(s) : Fernandez-Lopez L , Cea-Rama I , Alvarez-Malmagro J , Ressmann AK , Gonzalez-Alfonso JL , Coscolin C , Shahgaldian P , Plou FJ , Modregger J , Pita M , Sanz-Aparicio J , Ferrer M |
| Ref : Chem Commun (Camb) , : , 2023 |
| Abstract : Fernandez-Lopez_2023_Chem.Commun.(Camb)__ |
| ESTHER : Fernandez-Lopez_2023_Chem.Commun.(Camb)__ |
| PubMedSearch : Fernandez-Lopez_2023_Chem.Commun.(Camb)__ |
| PubMedID: 37376994 |
| Gene_locus related to this paper: 9zzzz-a0a2k8jn75 |