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Inhibitor Report for: WHP313

Broad spectrum inhibitor of serine hydrolases


General
Type Piperidine
Chemical_Nomenclature
Canonical SMILES C1=CC(=CC=C1Cl)CCC2CCN(CC2)C(=O)F
InChI InChI=1S/C14H17ClFNO/c15-13-5-3-11(4-6-13)1-2-12-7-9-17(10-8-12)14(16)18/h3-6,12H,1-2,7-10H2
InChIKey CLCJMFNMJNRXEJ-UHFFFAOYSA-N
Other name(s)
________________________________________________________________________________________________
MW|269.74
Formula|C14H17ClFNO
CAS_number|
PubChem|
UniChem|CLCJMFNMJNRXEJ-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | WHP313 ligand of proteins in family: S9N_PREPL_Peptidase_S9
Protein | human-PREPL

References:
Search PubMed for references concerning: WHP313
    Title: Prolyl endopeptidase-like is a (thio)esterase involved in mitochondrial respiratory chain function
    Rosier K, McDevitt MT, Smet J, Floyd BJ, Verschoore M, Marcaida MJ, Bingman CA, Lemmens I, Dal Peraro M and Creemers JWM <12 more author(s)>
    Ref: iScience, 24:103460, 2021 : PubMed