Tyramine

An indirect sympathomimetic. Tyramine does not directly activate adrenergic receptors, but it can serve as a substrate for adrenergic uptake systems and monoamine oxidase so it prolongs the actions of adrenergic transmitters. It also provokes transmitter release from adrenergic terminals. Tyramine may be a neurotransmitter in some invertebrate nervous systems.

General

Type : Adrenergic Uptake Inhibitors,Not A\/B H target,Drug

Chemical_Nomenclature : 4-(2-aminoethyl)phenol

Canonical SMILES : C1=CC(=CC=C1CCN)O

InChI : InChI=1S\/C8H11NO\/c9-6-5-7-1-3-8(10)4-2-7\/h1-4,10H,5-6,9H2

InChIKey : DZGWFCGJZKJUFP-UHFFFAOYSA-N

Other name(s) : Tyramin,Tyrosamine,Systogene,Uteramine,Tocosine,p-Tyramine,Tenosin-wirkstoff,Tyramine base,p-Hydroxyphenethylamine


MW : 137.179

Formula : C8H11NO

CAS_number :

PubChem : 5610

UniChem : DZGWFCGJZKJUFP-UHFFFAOYSA-N

IUPHAR :

Wikipedia : Tyramine

Target

Families : Tyramine ligand of proteins in family: BCHE

Stucture :

Protein :

References (4)

Title : Serum butyrylcholinesterase of non-human primate shows amine sensitive aryl acyl amidase and metallopeptidase activities and characteristics similar to those of the human serum enzyme - Bhanumathy_1998_Indian.J.Biochem.Biophys_35_148
Author(s) : Bhanumathy CD , Rao RV , Balasubramanian AS
Ref : Indian J Biochem Biophys , 35 :148 , 1998
Abstract : Bhanumathy_1998_Indian.J.Biochem.Biophys_35_148
ESTHER : Bhanumathy_1998_Indian.J.Biochem.Biophys_35_148
PubMedSearch : Bhanumathy_1998_Indian.J.Biochem.Biophys_35_148
PubMedID: 9803663

Title : Cholinesterases exhibiting aryl acylamidase activity in human amniotic fluid - Jayanthi_1992_Clin.Chim.Acta_205_157
Author(s) : Jayanthi LD , Balasubramanian N , Balasubramanian AS
Ref : Clinica Chimica Acta , 205 :157 , 1992
Abstract : Jayanthi_1992_Clin.Chim.Acta_205_157
ESTHER : Jayanthi_1992_Clin.Chim.Acta_205_157
PubMedSearch : Jayanthi_1992_Clin.Chim.Acta_205_157
PubMedID: 1349516

Title : Human cerebrospinal fluid acetylcholinesterase and butyrylcholinesterase. Evidence for identity between the serum and cerebrospinal fluid butyrylcholinesterase - Rao_1989_Clin.Chim.Acta_183_135
Author(s) : Rao RV , Gnanamuthu C , Balasubramanian AS
Ref : Clinica Chimica Acta , 183 :135 , 1989
Abstract : Rao_1989_Clin.Chim.Acta_183_135
ESTHER : Rao_1989_Clin.Chim.Acta_183_135
PubMedSearch : Rao_1989_Clin.Chim.Acta_183_135
PubMedID: 2791303

Title : The aryl acylamidases and their relationship to cholinesterases in human serum, erythrocyte and liver - George_1981_Eur.J.Biochem_121_177
Author(s) : George ST , Balasubramanian AS
Ref : European Journal of Biochemistry , 121 :177 , 1981
Abstract : George_1981_Eur.J.Biochem_121_177
ESTHER : George_1981_Eur.J.Biochem_121_177
PubMedSearch : George_1981_Eur.J.Biochem_121_177
PubMedID: 7035166