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TMPS

Impurity in malathion extremely toxic for mammals, structural isomer of TMP

General

Type : Organophosphate,Sulfur Compound

Chemical_Nomenclature : trimethoxy(sulfanylidene)-$l^{5}-phosphane

Canonical SMILES : COP(=S)(OC)OC

InChI : InChI=1S\/C3H9O3PS\/c1-4-7(8,5-2)6-3\/h1-3H3

InChIKey : XWSLYQXUTWUIKM-UHFFFAOYSA-N

Other name(s) : O,O,O-Trimethyl phosphorothioate,TMP=S,trimethoxy-sulfanylidene-phosphorane,Trimethyl thiophosphate,Trimethylthiophosphate,Trimethyl thionophosphate,O,O,O-Trimethylthiofosfat,Trimethoxyphosphine Sulfide,O,O,O-Trimethyl thiophosphate

MW : 156.142

Formula : C3H9O3PS

CAS_number : 152-18-1

PubChem : 9038

UniChem : XWSLYQXUTWUIKM-UHFFFAOYSA-N

Target

Families : TMPS ligand of proteins in family
ACHE

References (3)

Title : Synthesis and 31P chemical shift identification of tripeptide active site models that represent human serum acetylcholinesterase covalently modified at serine by certain organophosphates - Thompson_1996_Chem.Res.Toxicol_9_1325
Author(s) : Thompson CM , Suarez AI , Rodriguez OP
Ref : Chemical Research in Toxicology , 9 :1325 , 1996
Abstract : Thompson_1996_Chem.Res.Toxicol_9_1325
ESTHER : Thompson_1996_Chem.Res.Toxicol_9_1325
PubMedSearch : Thompson_1996_Chem.Res.Toxicol_9_1325
PubMedID: 8951236

Title : Mutagenic and alkylating activities of organophosphate impurities of commercial malathion - Imamura_1985_Mutat.Res_155_1
Author(s) : Imamura T , Talcott RE
Ref : Mutat Res , 155 :1 , 1985
Abstract : Imamura_1985_Mutat.Res_155_1
ESTHER : Imamura_1985_Mutat.Res_155_1
PubMedSearch : Imamura_1985_Mutat.Res_155_1
PubMedID: 3881662

Title : Toxicological properties of trialkyl phosphorothioate and dialkyl alkyl- and arylphosphonothioate esters - Fukuto_1983_J.Environ.Sci.Health.B_18_89
Author(s) : Fukuto TR
Ref : J Environ Sci Health B , 18 :89 , 1983
Abstract : Fukuto_1983_J.Environ.Sci.Health.B_18_89
ESTHER : Fukuto_1983_J.Environ.Sci.Health.B_18_89
PubMedSearch : Fukuto_1983_J.Environ.Sci.Health.B_18_89
PubMedID: 6833715 
Array
(
    [id] => 5703
    [inhibitor] => TMPS
    [type] => Array
        (
            [0] => Organophosphate
            [1] => Sulfur Compound
        )

    [other_name] => Array
        (
            [0] => O,O,O-Trimethyl phosphorothioate
            [1] => TMP=S
            [2] => trimethoxy-sulfanylidene-phosphorane
            [3] => Trimethyl thiophosphate
            [4] => Trimethylthiophosphate
            [5] => Trimethyl thionophosphate
            [6] => O,O,O-Trimethylthiofosfat
            [7] => Trimethoxyphosphine Sulfide
            [8] => O,O,O-Trimethyl thiophosphate
        )

    [chemical_nomenclature] => trimethoxy(sulfanylidene)-$l^{5}-phosphane
    [formula] => C3H9O3PS
    [cas_number] => 152-18-1
    [mw] => 156.142
    [pick_me_to_call] => display_script
    [kinetic_parameter] => 
    [paper] => Fukuto_1983_J.Environ.Sci.Health.B_18_89 || Imamura_1985_Mutat.Res_155_1 || Thompson_1996_Chem.Res.Toxicol_9_1325
    [comment] => Impurity in malathion extremely toxic for mammals, structural isomer of TMP 
    [gene_locus] => 
    [kin_inhibitor] => 
    [cid] => 9038
    [family] => ACHE
    [inchikey] => XWSLYQXUTWUIKM-UHFFFAOYSA-N
    [canonicalsmiles] => COP(=S)(OC)OC
    [inchi] => InChI=1S\/C3H9O3PS\/c1-4-7(8,5-2)6-3\/h1-3H3
    [wikipedia] => 
    [iupharlig] => 
    [structure] => 
    [substrate] => 
    [interact_gene_locus] => 
    [mutation] => 
    [comment2] => 
    [extoxnet] => 
    [news] => 
    [theoretical_model] => 
)