Inhibitor Report for: TDZD8

An experimental compound which was being developed for the potential treatment of Alzheimer's disease. It has a role as an EC 2.7.11.26 (tau-protein kinase) inhibitor, an apoptosis inducer, an antineoplastic agent, a neuroprotective agent and an anti-inflammatory agent.

General

Type		Not A/B H target, GSK-3 kinase inhibitor, Thiadiazol
Chemical_Nomenclature		4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione
Canonical SMILES		CN1C(=O)N(C(=O)S1)CC2=CC=CC=C2
InChI		InChI=1S/C10H10N2O2S/c1-11-9(13)12(10(14)15-11)7-8-5-3-2-4-6-8/h2-6H,7H2,1H3
InChIKey		JDSJDASOXWCHPN-UHFFFAOYSA-N
Other name(s)		U3W ; TDZD-8 ; GSK-3beta Inhibitor I ; TDZD 8 ; SCHEMBL139834 ; ZINC27361 ; CHEBI:147411

________________________________________________________________________________________________

MW	\|	222.27
Formula	\|	C10H10N2O2S
CAS_number	\|	327036-89-5
PubChem	\|	4124851
UniChem	\|	JDSJDASOXWCHPN-UHFFFAOYSA-N
IUPHAR	\|
Wikipedia	\|

Target

Families	\|	TDZD8 ligand of proteins in family: Pectinacetylesterase-Notum
Stucture	\|	1 structure: 7BMD: Human Notum TDZD8 complex
Protein	\|	human-NOTUM

References:

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