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Inhibitor Report for: TAM1

General
Type Piperidine, Benzofuran
Chemical_Nomenclature ethyl 5-hydroxy-4-[(4-methylpiperidin-1-yl)methyl]-2-phenyl-1-benzofuran-3-carboxylate
Canonical SMILES CCOC(=O)C1=C(OC2=C1C(=C(C=C2)O)CN3CCC(CC3)C)C4=CC=CC=C4
InChI InChI=1S/C24H27NO4/c1-3-28-24(27)22-21-18(15-25-13-11-16(2)12-14-25)19(26)9-10-20(21)29-23(22)17-7-5-4-6-8-17/h4-10,16,26H,3,11-15H2,1-2H3
InChIKey YDARBKORYFGQMH-UHFFFAOYSA-N
Other name(s) 301682-60-0 ; AC1M1STI ; UNM000000584101 ; AC1Q33NV ; Oprea1_203624
________________________________________________________________________________________________
MW|393.48
Formula|C24H27NO4
CAS_number|
PubChem|2129850
UniChem|YDARBKORYFGQMH-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | TAM1 ligand of proteins in family: Thioesterase
Stucture | 1 structure: 5V3X: Crystal Structure of Mtb Pks13 Thioesterase domain in complex with inhibitor TAM1
Protein | myctu-PKS13

References:
Search PubMed for references concerning: TAM1
    Title: Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13
    Aggarwal A, Parai MK, Shetty N, Wallis D, Woolhiser L, Hastings C, Dutta NK, Galaviz S, Dhakal RC and Sacchettini JC <20 more author(s)>
    Ref: Cell, 170:249, 2017 : PubMed