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T-82(2)

see papers Isoma_2002_Jpn.J.Pharmacol_88_206 and Isomae_2003_Eur.J.Pharmacol_465_97 but not the same compound

General

Type : Piperazine,Phenothiazine,Benzoate,Sulfur Compound

Chemical_Nomenclature : 2-[4-[3-(3-chlorophenothiazin-10-yl)propyl]piperazin-1-yl]ethyl 3,4,5-trimethoxybenzoate

Canonical SMILES : COC1=CC(=CC(=C1OC)OC)C(=O)OCCN2CCN(CC2)CCCN3C4=C(C=C(C=C4)Cl)SC5=CC=CC=C53

InChI : InChI=1S\/C31H36ClN3O5S\/c1-37-26-19-22(20-27(38-2)30(26)39-3)31(36)40-18-17-34-15-13-33(14-16-34)11-6-12-35-24-7-4-5-8-28(24)41-29-21-23(32)9-10-25(29)35\/h4-5,7-10,19-21H,6,11-18H2,1-3H3

InChIKey : KZAJTVRKNKAXAG-UHFFFAOYSA-N

Other name(s) : T-82,T 82,3,4,5-Trimethoxybenzoic acid, 2-(4-(3-(3-chloro-10H-phenothiazin-10-yl)propyl)-1-piperazinyl)ethyl ester,3-Chloro-6-(4'-hydroxyethylpiperazinyl)-1,1-propylphenothiazine 3'',4'',45''-trimethoxybenzoic acid,AC1L4VYE,AC1Q682F,CTK4H9992

MW : 598.153

Formula : C31H36ClN3O5S

CAS_number : 38455-99-1 || 132236-18-1

PubChem : 193285

UniChem : KZAJTVRKNKAXAG-UHFFFAOYSA-N

IUPHAR :

Wikipedia :

Target

Families : T-82(2) ligand of proteins in family: ACHE

Stucture :

Protein :

References (1)

Title : Effects of T-82, a new quinoline derivative, on cholinesterase activity and extracellular acetylcholine concentration in rat brain - Isoma_2002_Jpn.J.Pharmacol_88_206
Author(s) : Isoma K , Ishikawa M , Ohta M , Ogawa Y , Hasegawa H , Kohda T , Kamei J
Ref : Japanese Journal of Pharmacology , 88 :206 , 2002
Abstract : Isoma_2002_Jpn.J.Pharmacol_88_206
ESTHER : Isoma_2002_Jpn.J.Pharmacol_88_206
PubMedSearch : Isoma_2002_Jpn.J.Pharmacol_88_206
PubMedID: 11928722