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Inhibitor Report for: Suronacrine

Has weaker anticholinesterase actions that are masked by cholinoceptor blockade


General
Type Acridine
Chemical_Nomenclature 9-benzylamino-1,2,3,4-tetrahydroacridin-1-ol maleate ; 1-Acridinol, 1,2,3,4-tetrahydro-9-((phenylmethyl)amino)-
Canonical SMILES C1CC(C2=C(C3=CC=CC=C3N=C2C1)NCC4=CC=CC=C4)O
InChI InChI=1S/C20H20N2O/c23-18-12-6-11-17-19(18)20(15-9-4-5-10-16(15)22-17)21-13-14-7-2-1-3-8-14/h1-5,7-10,18,23H,6,11-13H2,(H,21,22)
InChIKey HERUZAOANPGYSY-UHFFFAOYSA-N
Other name(s) Suronacrinum ; HOE-427 ; HP-128
________________________________________________________________________________________________
MW|304.386
Formula|C20-H20-N2-O
CAS_number|104675-35-6
PubChem|60601
UniChem|HERUZAOANPGYSY-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | Suronacrine ligand of proteins in family: ACHE

References:
Search PubMed for references concerning: Suronacrine
    Title: Effects of tacrine, velnacrine (HP029), suronacrine (HP128), and 3,4-diaminopyridine on skeletal neuromuscular transmission in vitro
    Braga MF, Harvey AL, Rowan EG
    Ref: British Journal of Pharmacology, 102:909, 1991 : PubMed