Soman

Nerve agent GD

General

Type : Chemical Warfare Agent,Organophosphate,Nerve Agent G-series,Derivative of Soman

Chemical_Nomenclature : 3-[fluoro(methyl)phosphoryl]oxy-2,2-dimethylbutane

Canonical SMILES : CC(C(C)(C)C)OP(=O)(C)F

InChI : InChI=1S\/C7H16FO2P\/c1-6(7(2,3)4)10-11(5,8)9\/h6H,1-5H3

InChIKey : GRXKLBBBQUKJJZ-UHFFFAOYSA-N

Other name(s) : Pinacolylmethylphosphonofluoridate,Pinacolyloxymethylphosphorylfluoride,Methylphosphonofluoridic acid, 1,2,2-trimethylpropyl ester,GD,ZINC000038494900


MW : 182.19

Formula : C7H16FO2P

CAS_number : 96-64-0

PubChem : 7305

UniChem : GRXKLBBBQUKJJZ-UHFFFAOYSA-N

IUPHAR :

Wikipedia : Soman

References (85)

Title : Enzymatic Decontamination of G-Type, V-Type and Novichok Nerve Agents - Jacquet_2021_Int.J.Mol.Sci_22_
Author(s) : Jacquet P , Remy B , Bross RPT , van Grol M , Gaucher F , Chabriere E , De Koning MC , Daude D
Ref : Int J Mol Sci , 22 : , 2021
Abstract : Jacquet_2021_Int.J.Mol.Sci_22_
ESTHER : Jacquet_2021_Int.J.Mol.Sci_22_
PubMedSearch : Jacquet_2021_Int.J.Mol.Sci_22_
PubMedID: 34360916

Title : Structural and Biochemical Insights into the Inhibition of Human Acetylcholinesterase by G-Series Nerve Agents and Subsequent Reactivation by HI-6 - McGuire_2021_Chem.Res.Toxicol_34_804
Author(s) : McGuire JR , Bester SM , Guelta MA , Cheung J , Langley C , Winemiller MD , Bae SY , Funk V , Myslinski JM , Pegan SD , Height JJ
Ref : Chemical Research in Toxicology , 34 :804 , 2021
Abstract : McGuire_2021_Chem.Res.Toxicol_34_804
ESTHER : McGuire_2021_Chem.Res.Toxicol_34_804
PubMedSearch : McGuire_2021_Chem.Res.Toxicol_34_804
PubMedID: 33538594
Gene_locus related to this paper: human-ACHE

Title : Structural and Kinetic Evidence of Aging after Organophosphate Inhibition of Human Cathepsin A - Bouknight_2020_Biochem.Pharmacol__113980
Author(s) : Bouknight KD , Jurkouich KM , Compton JR , Khavrutskii IV , Guelta MA , Harvey SP , Legler PM
Ref : Biochemical Pharmacology , :113980 , 2020
Abstract : Bouknight_2020_Biochem.Pharmacol__113980
ESTHER : Bouknight_2020_Biochem.Pharmacol__113980
PubMedSearch : Bouknight_2020_Biochem.Pharmacol__113980
PubMedID: 32305437
Gene_locus related to this paper: human-CTSA

Title : A step toward the reactivation of aged cholinesterases - Crystal structure of ligands binding to aged human butyrylcholinesterase - Wandhammer_2013_Chem.Biol.Interact_203_19
Author(s) : Wandhammer M , De Koning MC , van Grol M , Loiodice M , Saurel L , Noort D , Goeldner M , Nachon F
Ref : Chemico-Biological Interactions , 203 :19 , 2013
Abstract : Wandhammer_2013_Chem.Biol.Interact_203_19
ESTHER : Wandhammer_2013_Chem.Biol.Interact_203_19
PubMedSearch : Wandhammer_2013_Chem.Biol.Interact_203_19
PubMedID: 22922115
Gene_locus related to this paper: human-BCHE

Title : In vitro kinetic interactions of pyridostigmine, physostigmine and soman with erythrocyte and muscle acetylcholinesterase from different species - Herkert_2011_Toxicol.Lett_206_41
Author(s) : Herkert NM , Thiermann H , Worek F
Ref : Toxicol Lett , 206 :41 , 2011
Abstract : Herkert_2011_Toxicol.Lett_206_41
ESTHER : Herkert_2011_Toxicol.Lett_206_41
PubMedSearch : Herkert_2011_Toxicol.Lett_206_41
PubMedID: 21414391

Title : Crystallographic snapshots of nonaged and aged conjugates of soman with acetylcholinesterase, and of a ternary complex of the aged conjugate with pralidoxime - Sanson_2009_J.Med.Chem_52_7593
Author(s) : Sanson B , Nachon F , Colletier JP , Froment MT , Toker L , Greenblatt HM , Sussman JL , Ashani Y , Masson P , Silman I , Weik M
Ref : Journal of Medicinal Chemistry , 52 :7593 , 2009
Abstract : Sanson_2009_J.Med.Chem_52_7593
ESTHER : Sanson_2009_J.Med.Chem_52_7593
PubMedSearch : Sanson_2009_J.Med.Chem_52_7593
PubMedID: 19642642
Gene_locus related to this paper: torca-ACHE

Title : Crystal structures of human carboxylesterase 1 in covalent complexes with the chemical warfare agents soman and tabun - Fleming_2007_Biochemistry_46_5063
Author(s) : Fleming CD , Edwards CC , Kirby SD , Maxwell DM , Potter PM , Cerasoli DM , Redinbo MR
Ref : Biochemistry , 46 :5063 , 2007
Abstract : Fleming_2007_Biochemistry_46_5063
ESTHER : Fleming_2007_Biochemistry_46_5063
PubMedSearch : Fleming_2007_Biochemistry_46_5063
PubMedID: 17407327
Gene_locus related to this paper: human-CES1

Title : Enzyme-kinetic investigation of different sarin analogues reacting with human acetylcholinesterase and butyrylcholinesterase - Bartling_2007_Toxicology_233_166
Author(s) : Bartling A , Worek F , Szinicz L , Thiermann H
Ref : Toxicology , 233 :166 , 2007
Abstract : Bartling_2007_Toxicology_233_166
ESTHER : Bartling_2007_Toxicology_233_166
PubMedSearch : Bartling_2007_Toxicology_233_166
PubMedID: 16904809

Title : Crystal structure of human butyrylcholinesterase and of its complexes with substrate and products - Nicolet_2003_J.Biol.Chem_278_41141
Author(s) : Nicolet Y , Lockridge O , Masson P , Fontecilla-Camps JC , Nachon F
Ref : Journal of Biological Chemistry , 278 :41141 , 2003
Abstract : Nicolet_2003_J.Biol.Chem_278_41141
ESTHER : Nicolet_2003_J.Biol.Chem_278_41141
PubMedSearch : Nicolet_2003_J.Biol.Chem_278_41141
PubMedID: 12869558
Gene_locus related to this paper: human-BCHE

Title : A comparison of the efficacy of a new asymmetric bispyridinium oxime BI-6 with currently available oximes and H oximes against soman by in vitro and in vivo methods - Kassa_1999_Toxicology_132_111
Author(s) : Kassa J , Cabal J
Ref : Toxicology , 132 :111 , 1999
Abstract : Kassa_1999_Toxicology_132_111
ESTHER : Kassa_1999_Toxicology_132_111
PubMedSearch : Kassa_1999_Toxicology_132_111
PubMedID: 10433374

Title : Crystal structures of aged phosphonylated acetylcholinesterase: nerve agent reaction products at the atomic level - Millard_1999_Biochemistry_38_7032
Author(s) : Millard CB , Kryger G , Ordentlich A , Greenblatt HM , Harel M , Raves ML , Segall Y , Barak D , Shafferman A , Silman I , Sussman JL
Ref : Biochemistry , 38 :7032 , 1999
Abstract : Millard_1999_Biochemistry_38_7032
ESTHER : Millard_1999_Biochemistry_38_7032
PubMedSearch : Millard_1999_Biochemistry_38_7032
PubMedID: 10353814
Gene_locus related to this paper: torca-ACHE

Title : Effects of various drugs including organophosphorus compounds (OPC) and therapeutic compounds against OPC on DRL responding - Bizot_1998_Pharmacol.Biochem.Behav_59_1069
Author(s) : Bizot JC
Ref : Pharmacol Biochem Behav , 59 :1069 , 1998
Abstract : Bizot_1998_Pharmacol.Biochem.Behav_59_1069
ESTHER : Bizot_1998_Pharmacol.Biochem.Behav_59_1069
PubMedSearch : Bizot_1998_Pharmacol.Biochem.Behav_59_1069
PubMedID: 9586869

Title : Inhibition by soman of NMDA-stimulated [3H]norepinephrine release from rat cortical slices, studies of non-cholinergic effect - Tang_1998_Brain.Res_787_123
Author(s) : Tang HW , Cassel G
Ref : Brain Research , 787 :123 , 1998
Abstract : Tang_1998_Brain.Res_787_123
ESTHER : Tang_1998_Brain.Res_787_123
PubMedSearch : Tang_1998_Brain.Res_787_123
PubMedID: 9518577

Title : Electrocorticographic changes during generalized convulsive status epilepticus in soman intoxicated rats - Koplovitz_1998_Epilepsy.Res_30_159
Author(s) : Koplovitz I , Skvorak JP
Ref : Epilepsy Research , 30 :159 , 1998
Abstract : Koplovitz_1998_Epilepsy.Res_30_159
ESTHER : Koplovitz_1998_Epilepsy.Res_30_159
PubMedSearch : Koplovitz_1998_Epilepsy.Res_30_159
PubMedID: 9600547

Title : A comparison of the efficacy of new asymmetric bispyridinium oxime BI-6 with other oximes (obidoxime, HI-6) against soman in rats - Kassa_1998_Hum.Exp.Toxicol_17_331
Author(s) : Kassa J
Ref : Hum Exp Toxicol , 17 :331 , 1998
Abstract : Kassa_1998_Hum.Exp.Toxicol_17_331
ESTHER : Kassa_1998_Hum.Exp.Toxicol_17_331
PubMedSearch : Kassa_1998_Hum.Exp.Toxicol_17_331
PubMedID: 9688357

Title : Prophylaxis against soman inhalation toxicity in guinea pigs by pretreatment alone with human serum butyrylcholinesterase - Allon_1998_Toxicol.Sci_43_121
Author(s) : Allon N , Raveh L , Gilat E , Cohen E , Grunwald J , Ashani Y
Ref : Toxicol Sci , 43 :121 , 1998
Abstract : Allon_1998_Toxicol.Sci_43_121
ESTHER : Allon_1998_Toxicol.Sci_43_121
PubMedSearch : Allon_1998_Toxicol.Sci_43_121
PubMedID: 9710953

Title : Organophosphorus acid anhydride hydrolase activity in human butyrylcholinesterase: synergy results in a somanase - Millard_1998_Biochemistry_37_237
Author(s) : Millard CB , Lockridge O , Broomfield CA
Ref : Biochemistry , 37 :237 , 1998
Abstract : Millard_1998_Biochemistry_37_237
ESTHER : Millard_1998_Biochemistry_37_237
PubMedSearch : Millard_1998_Biochemistry_37_237
PubMedID: 9425044
Gene_locus related to this paper: human-BCHE

Title : Reactivating potency of obidoxime, pralidoxime, HI 6 and HLo 7 in human erythrocyte acetylcholinesterase inhibited by highly toxic organophosphorus compounds - Worek_1998_Arch.Toxicol_72_237
Author(s) : Worek F , Widmann R , Knopff O , Szinicz L
Ref : Archives of Toxicology , 72 :237 , 1998
Abstract : Worek_1998_Arch.Toxicol_72_237
ESTHER : Worek_1998_Arch.Toxicol_72_237
PubMedSearch : Worek_1998_Arch.Toxicol_72_237
PubMedID: 9587020

Title : Inhalation toxicokinetics of soman stereoisomers in the atropinized guinea pig with nose-only exposure to soman vapor - Langenberg_1998_Toxicol.Appl.Pharmacol_151_79
Author(s) : Langenberg JP , Spruit HE , van der Wiel HJ , Trap HC , Helmich RB , Bergers WW , van Helden HP , Benschop HP
Ref : Toxicol Appl Pharmacol , 151 :79 , 1998
Abstract : Langenberg_1998_Toxicol.Appl.Pharmacol_151_79
ESTHER : Langenberg_1998_Toxicol.Appl.Pharmacol_151_79
PubMedSearch : Langenberg_1998_Toxicol.Appl.Pharmacol_151_79
PubMedID: 9705889

Title : Mapping of cerebral metabolic activation in three models of cholinergic convulsions - Scremin_1998_Brain.Res.Bull_45_167
Author(s) : Scremin OU , Shih TM , Li MG , Jenden DJ
Ref : Brain Research Bulletin , 45 :167 , 1998
Abstract : Scremin_1998_Brain.Res.Bull_45_167
ESTHER : Scremin_1998_Brain.Res.Bull_45_167
PubMedSearch : Scremin_1998_Brain.Res.Bull_45_167
PubMedID: 9443835

Title : Unique push-pull mechanism of dealkylation in soman-inhibited cholinesterases - Viragh_1997_Biochemistry_36_8243
Author(s) : Viragh C , Akhmetshin R , Kovach IM , Broomfield CA
Ref : Biochemistry , 36 :8243 , 1997
Abstract : Viragh_1997_Biochemistry_36_8243
ESTHER : Viragh_1997_Biochemistry_36_8243
PubMedSearch : Viragh_1997_Biochemistry_36_8243
PubMedID: 9204869

Title : Correlation between cortical EEG and striatal microdialysis in soman- intoxicated rats - Jacobsson_1997_Neurosci.Lett_231_155
Author(s) : Jacobsson SO , Sellstrom A , Persson SA , Cassel GE
Ref : Neuroscience Letters , 231 :155 , 1997
Abstract : Jacobsson_1997_Neurosci.Lett_231_155
ESTHER : Jacobsson_1997_Neurosci.Lett_231_155
PubMedSearch : Jacobsson_1997_Neurosci.Lett_231_155
PubMedID: 9300645

Title : [The effect of parasympatholytics on the therapeutic effectiveness of the oxime HI-6 against organophosphorus compounds (Soman, substance VX, Fosdrin) in mice] - Kassa_1997_Cas.Lek.Cesk_136_124
Author(s) : Kassa J , Vachek J
Ref : Casopis Lekaru Ceskych , 136 :124 , 1997
Abstract : Kassa_1997_Cas.Lek.Cesk_136_124
ESTHER : Kassa_1997_Cas.Lek.Cesk_136_124
PubMedSearch : Kassa_1997_Cas.Lek.Cesk_136_124
PubMedID: 9221183

Title : Pharmacokinetics and effects of HI 6 in blood and brain of soman-intoxicated rats: a microdialysis study - Cassel_1997_Eur.J.Pharmacol_332_43
Author(s) : Cassel G , Karlsson L , Waara L , Ang KW , Goransson-Nyberg A
Ref : European Journal of Pharmacology , 332 :43 , 1997
Abstract : Cassel_1997_Eur.J.Pharmacol_332_43
ESTHER : Cassel_1997_Eur.J.Pharmacol_332_43
PubMedSearch : Cassel_1997_Eur.J.Pharmacol_332_43
PubMedID: 9298924

Title : [Acute poisoning by neuroparalytic agents and its long-term effects] - Ianno_1997_Med.Tr.Prom.Ekol_6_5
Author(s) : Ianno LV , Musiichuk Iu I
Ref : Med Tr Prom Ekol , 6 :5 , 1997
Abstract : Ianno_1997_Med.Tr.Prom.Ekol_6_5
ESTHER : Ianno_1997_Med.Tr.Prom.Ekol_6_5
PubMedSearch : Ianno_1997_Med.Tr.Prom.Ekol_6_5
PubMedID: 9273141

Title : Differential inhibition of the brain acetylcholinesterase molecular forms following sarin, soman and VX intoxication in laboratory rats - Bajgar_1997_Acta.Medica_40_89
Author(s) : Bajgar J
Ref : Acta Medica , 40 :89 , 1997
Abstract : Bajgar_1997_Acta.Medica_40_89
ESTHER : Bajgar_1997_Acta.Medica_40_89
PubMedSearch : Bajgar_1997_Acta.Medica_40_89
PubMedID: 9481881

Title : Mutant acetylcholinesterases as potential detoxification agents for organophosphate poisoning - Saxena_1997_Biochem.Pharmacol_54_269
Author(s) : Saxena A , Maxwell DM , Quinn DM , Radic Z , Taylor P , Doctor BP
Ref : Biochemical Pharmacology , 54 :269 , 1997
Abstract : Saxena_1997_Biochem.Pharmacol_54_269
ESTHER : Saxena_1997_Biochem.Pharmacol_54_269
PubMedSearch : Saxena_1997_Biochem.Pharmacol_54_269
PubMedID: 9271331

Title : Substrate dependence of amiloride- and soman-induced conformation changes of butyrylcholinesterase as evidenced by high-pressure perturbation - Clery_1995_Biochim.Biophys.Acta_1250_19
Author(s) : Clery C , Heiber-Langer I , Channac L , David L , Balny C , Masson P
Ref : Biochimica & Biophysica Acta , 1250 :19 , 1995
Abstract : Clery_1995_Biochim.Biophys.Acta_1250_19
ESTHER : Clery_1995_Biochim.Biophys.Acta_1250_19
PubMedSearch : Clery_1995_Biochim.Biophys.Acta_1250_19
PubMedID: 7612649

Title : Origins and diversity of the aging reaction in phosphonate adducts of serine hydrolase enzymes: what characteristics of the active site do they probe? - Bencsura_1995_Biochemistry_34_8989
Author(s) : Bencsura A , Enyedy IJ , Kovach IM
Ref : Biochemistry , 34 :8989 , 1995
Abstract : Bencsura_1995_Biochemistry_34_8989
ESTHER : Bencsura_1995_Biochemistry_34_8989
PubMedSearch : Bencsura_1995_Biochemistry_34_8989
PubMedID: 7619798

Title : Comparison of efficacy of two oximes (HI-6 and obidoxime) in soman poisoning in rats - Kassa_1995_Toxicology_101_167
Author(s) : Kassa J
Ref : Toxicology , 101 :167 , 1995
Abstract : Kassa_1995_Toxicology_101_167
ESTHER : Kassa_1995_Toxicology_101_167
PubMedSearch : Kassa_1995_Toxicology_101_167
PubMedID: 7676463

Title : [Comparison of the effect of selected cholinesterase reactivators combined with atropine on soman and fosdrin toxicity in mice] - Kassa_1995_Sb.Ved.Pr.Lek.Fak.Karlovy.Univerzity.Hradci.Kralove.Suppl_38_63
Author(s) : Kassa J
Ref : Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove Suppl , 38 :63 , 1995
Abstract : Kassa_1995_Sb.Ved.Pr.Lek.Fak.Karlovy.Univerzity.Hradci.Kralove.Suppl_38_63
ESTHER : Kassa_1995_Sb.Ved.Pr.Lek.Fak.Karlovy.Univerzity.Hradci.Kralove.Suppl_38_63
PubMedSearch : Kassa_1995_Sb.Ved.Pr.Lek.Fak.Karlovy.Univerzity.Hradci.Kralove.Suppl_38_63
PubMedID: 9441373

Title : Prophylactic transdermal treatment with physostigmine and scopolamine against soman intoxication in guinea-pigs - Meshulam_1995_J.Appl.Toxicol_15_263
Author(s) : Meshulam Y , Davidovici R , Wengier A , Levy A
Ref : Journal of Applied Toxicology , 15 :263 , 1995
Abstract : Meshulam_1995_J.Appl.Toxicol_15_263
ESTHER : Meshulam_1995_J.Appl.Toxicol_15_263
PubMedSearch : Meshulam_1995_J.Appl.Toxicol_15_263
PubMedID: 7594194

Title : [Decontamination with clay or alcoholate of pigs percutaneously poisoned with VX and soman] - Knezevic_1994_Vojnosanit.Pregl_51_488
Author(s) : Knezevic DL , Tadic V
Ref : Vojnosanit Pregl , 51 :488 , 1994
Abstract : Knezevic_1994_Vojnosanit.Pregl_51_488
ESTHER : Knezevic_1994_Vojnosanit.Pregl_51_488
PubMedSearch : Knezevic_1994_Vojnosanit.Pregl_51_488
PubMedID: 8585153

Title : The role of nitric oxide in the neuropathology in soman intoxication - Bouchaud_1994_Brain.Res_660_249
Author(s) : Bouchaud C , Chollat-Namy A , Duserre S , Delamanche IS
Ref : Brain Research , 660 :249 , 1994
Abstract : Bouchaud_1994_Brain.Res_660_249
ESTHER : Bouchaud_1994_Brain.Res_660_249
PubMedSearch : Bouchaud_1994_Brain.Res_660_249
PubMedID: 7529650

Title : In vitro oxime-induced reactivation of various molecular forms of soman-inhibited acetylcholinesterase in striated muscle from rat, monkey and human - Clement_1994_Arch.Toxicol_68_648
Author(s) : Clement JG , Erhardt N
Ref : Archives of Toxicology , 68 :648 , 1994
Abstract : Clement_1994_Arch.Toxicol_68_648
ESTHER : Clement_1994_Arch.Toxicol_68_648
PubMedSearch : Clement_1994_Arch.Toxicol_68_648
PubMedID: 7857205

Title : Phosphotriesterase--a promising candidate for use in detoxification of organophosphates - Tuovinen_1994_Fundam.Appl.Toxicol_23_578
Author(s) : Tuovinen K , Kaliste-Korhonen E , Raushel FM , Hanninen O
Ref : Fundamental & Applied Toxicology , 23 :578 , 1994
Abstract : Tuovinen_1994_Fundam.Appl.Toxicol_23_578
ESTHER : Tuovinen_1994_Fundam.Appl.Toxicol_23_578
PubMedSearch : Tuovinen_1994_Fundam.Appl.Toxicol_23_578
PubMedID: 7867909

Title : Toxicokinetics of soman stereoisomers after subcutaneous administration to atropinized guinea pigs - Due_1994_Arch.Toxicol_68_60
Author(s) : Due AH , Trap HC , Langenberg JP , Benschop HP
Ref : Archives of Toxicology , 68 :60 , 1994
Abstract : Due_1994_Arch.Toxicol_68_60
ESTHER : Due_1994_Arch.Toxicol_68_60
PubMedSearch : Due_1994_Arch.Toxicol_68_60
PubMedID: 8166606

Title : Continuous administration of low dose rates of physostigmine and hyoscine to guinea-pigs prevents the toxicity and reduces the incapacitation produced by soman poisoning - Wetherell_1994_J.Pharm.Pharmacol_46_1023
Author(s) : Wetherell JR
Ref : J Pharm Pharmacol , 46 :1023 , 1994
Abstract : Wetherell_1994_J.Pharm.Pharmacol_46_1023
ESTHER : Wetherell_1994_J.Pharm.Pharmacol_46_1023
PubMedSearch : Wetherell_1994_J.Pharm.Pharmacol_46_1023
PubMedID: 7714714

Title : Primate performance decrements following acute soman exposure: failure of chemical countermeasures - Blick_1994_Pharmacol.Biochem.Behav_49_503
Author(s) : Blick DW , Murphy MR , Brown GC , Hartgraves SL
Ref : Pharmacology, Biochemistry & Behavior , 49 :503 , 1994
Abstract : Blick_1994_Pharmacol.Biochem.Behav_49_503
ESTHER : Blick_1994_Pharmacol.Biochem.Behav_49_503
PubMedSearch : Blick_1994_Pharmacol.Biochem.Behav_49_503
PubMedID: 7862701

Title : Comparison of several oximes on reactivation of soman-inhibited blood, brain and tissue cholinesterase activity in rats - Shih_1993_Arch.Toxicol_67_637
Author(s) : Shih TM
Ref : Archives of Toxicology , 67 :637 , 1993
Abstract : Shih_1993_Arch.Toxicol_67_637
ESTHER : Shih_1993_Arch.Toxicol_67_637
PubMedSearch : Shih_1993_Arch.Toxicol_67_637
PubMedID: 8311691

Title : Changes of rat blood and tissue cholinesterases following administration of tacrine derivatives in vivo - Bajgar_1993_Sb.Ved.Pr.Lek.Fak.Karlovy.Univerzity.Hradci.Kralove_36_73
Author(s) : Bajgar J , Skopec F
Ref : Sbornik Vedeckych Praci Lekarske Fakulty Karlovy Univerzity , 36 :73 , 1993
Abstract : Bajgar_1993_Sb.Ved.Pr.Lek.Fak.Karlovy.Univerzity.Hradci.Kralove_36_73
ESTHER : Bajgar_1993_Sb.Ved.Pr.Lek.Fak.Karlovy.Univerzity.Hradci.Kralove_36_73
PubMedSearch : Bajgar_1993_Sb.Ved.Pr.Lek.Fak.Karlovy.Univerzity.Hradci.Kralove_36_73
PubMedID: 8165433

Title : Immunochemical characterization of anti-acetylcholinesterase inhibitory monoclonal antibodies - Gentry_1993_Chem.Biol.Interact_87_227
Author(s) : Gentry MK , Saxena A , Ashani Y , Doctor BP
Ref : Chemico-Biological Interactions , 87 :227 , 1993
Abstract : Gentry_1993_Chem.Biol.Interact_87_227
ESTHER : Gentry_1993_Chem.Biol.Interact_87_227
PubMedSearch : Gentry_1993_Chem.Biol.Interact_87_227
PubMedID: 7688272

Title : Action of nerve agents to cholinesterases - Bajgar_1993_Sb.Ved.Pr.Lek.Fak.Karlovy.Univerzity.Hradci.Kralove_36_63
Author(s) : Bajgar J
Ref : Sbornik Vedeckych Praci Lekarske Fakulty Karlovy Univerzity , 36 :63 , 1993
Abstract : Bajgar_1993_Sb.Ved.Pr.Lek.Fak.Karlovy.Univerzity.Hradci.Kralove_36_63
ESTHER : Bajgar_1993_Sb.Ved.Pr.Lek.Fak.Karlovy.Univerzity.Hradci.Kralove_36_63
PubMedSearch : Bajgar_1993_Sb.Ved.Pr.Lek.Fak.Karlovy.Univerzity.Hradci.Kralove_36_63
PubMedID: 8165432

Title : Long-term effects of the anticholinesterases sarin and soman on latencies of muscle action potentials in mouse diaphragm muscle - Smith_1993_J.Pharm.Pharmacol_45_176
Author(s) : Smith AP
Ref : J Pharm Pharmacol , 45 :176 , 1993
Abstract : Smith_1993_J.Pharm.Pharmacol_45_176
ESTHER : Smith_1993_J.Pharm.Pharmacol_45_176
PubMedSearch : Smith_1993_J.Pharm.Pharmacol_45_176
PubMedID: 8097774

Title : Therapeutic efficacy of bis-pyridinium oximes against diisopropyl fluorophosphate (DFP) and soman intoxication in rodents -
Author(s) : Dube SN , Kumar D , Sikder AK , Sikder N , Jaiswal DK , Das Gupta S
Ref : Pharmazie , 47 :68 , 1992
PubMedID: 1608992

Title : Potential of memantine, D-tubocurarine, and atropine in preventing acute toxic myopathy induced by organophosphate nerve agents: soman, sarin, tabun and VX - Gupta_1992_Neurotoxicol_13_649
Author(s) : Gupta RC , Dettbarn WD
Ref : Neurotoxicology , 13 :649 , 1992
Abstract : Gupta_1992_Neurotoxicol_13_649
ESTHER : Gupta_1992_Neurotoxicol_13_649
PubMedSearch : Gupta_1992_Neurotoxicol_13_649
PubMedID: 1475066

Title : Successful pretreatment\/therapy of soman, sarin and VX intoxication - Lennox_1992_Drug.Chem.Toxicol_15_271
Author(s) : Lennox WJ , Harris LW , Anderson DR , Solana RP , Murrow ML , Wade JV
Ref : Drug & Chemical Toxicology , 15 :271 , 1992
Abstract : Lennox_1992_Drug.Chem.Toxicol_15_271
ESTHER : Lennox_1992_Drug.Chem.Toxicol_15_271
PubMedSearch : Lennox_1992_Drug.Chem.Toxicol_15_271
PubMedID: 1459040

Title : The effect of pyridostigmine pretreatment on oxime efficacy against intoxication by soman or VX in rats - Anderson_1992_Drug.Chem.Toxicol_15_285
Author(s) : Anderson DR , Harris LW , Woodard CL , Lennox WJ
Ref : Drug & Chemical Toxicology , 15 :285 , 1992
Abstract : Anderson_1992_Drug.Chem.Toxicol_15_285
ESTHER : Anderson_1992_Drug.Chem.Toxicol_15_285
PubMedSearch : Anderson_1992_Drug.Chem.Toxicol_15_285
PubMedID: 1459041

Title : Protection from lethality and behavioral incapacitation resulting from intoxication by soman (pinacolyl methylphosphonofluoridate) and treatment with atropine sulfate and 2-PAM chloride in the guinea pig, cavia porcellus - Romano_1991_Drug.Chem.Toxicol_14_21
Author(s) : Romano JA, Jr. , Terry MR , Murrow ML , Mays MZ
Ref : Drug & Chemical Toxicology , 14 :21 , 1991
Abstract : Romano_1991_Drug.Chem.Toxicol_14_21
ESTHER : Romano_1991_Drug.Chem.Toxicol_14_21
PubMedSearch : Romano_1991_Drug.Chem.Toxicol_14_21
PubMedID: 1889376

Title : Phosphylation kinetic constants and oxime-induced reactivation in acetylcholinesterase from fetal bovine serum, bovine caudate nucleus, and electric eel - Hanke_1991_J.Toxicol.Env.Health_34_141
Author(s) : Hanke DW , Overton MA
Ref : Journal of Toxicology & Environmental Health , 34 :141 , 1991
Abstract : Hanke_1991_J.Toxicol.Env.Health_34_141
ESTHER : Hanke_1991_J.Toxicol.Env.Health_34_141
PubMedSearch : Hanke_1991_J.Toxicol.Env.Health_34_141
PubMedID: 1890690

Title : Hypothermia: limited tolerance to repeated soman administration and cross-tolerance to oxotremorine - Clement_1991_Pharmacol.Biochem.Behav_39_305
Author(s) : Clement JG
Ref : Pharmacol Biochem Behav , 39 :305 , 1991
Abstract : Clement_1991_Pharmacol.Biochem.Behav_39_305
ESTHER : Clement_1991_Pharmacol.Biochem.Behav_39_305
PubMedSearch : Clement_1991_Pharmacol.Biochem.Behav_39_305
PubMedID: 1946573

Title : The effects of soman poisoning in combination with hypovolemic shock - Bottoms_1991_Fundam.Appl.Toxicol_16_622
Author(s) : Bottoms GD , Fessler JF , Pfeifer CA , Johnson M , Roesel OF , Voorhees WD
Ref : Fundamental & Applied Toxicology , 16 :622 , 1991
Abstract : Bottoms_1991_Fundam.Appl.Toxicol_16_622
ESTHER : Bottoms_1991_Fundam.Appl.Toxicol_16_622
PubMedSearch : Bottoms_1991_Fundam.Appl.Toxicol_16_622
PubMedID: 1884907

Title : Enzymes as pretreatment drugs for organophosphate toxicity - Doctor_1991_Neurosci.Biobehav.Rev_15_123
Author(s) : Doctor BP , Raveh L , Wolfe AD , Maxwell DM , Ashani Y
Ref : Neurosci Biobehav Rev , 15 :123 , 1991
Abstract : Doctor_1991_Neurosci.Biobehav.Rev_15_123
ESTHER : Doctor_1991_Neurosci.Biobehav.Rev_15_123
PubMedSearch : Doctor_1991_Neurosci.Biobehav.Rev_15_123
PubMedID: 2052184

Title : The effects of irreversible acetylcholinesterase inhibitors on transmission through sympathetic ganglia of the bullfrog - Heppner_1991_Neuropharmacol_30_843
Author(s) : Heppner TJ , Fiekers JF
Ref : Neuropharmacology , 30 :843 , 1991
Abstract : Heppner_1991_Neuropharmacol_30_843
ESTHER : Heppner_1991_Neuropharmacol_30_843
PubMedSearch : Heppner_1991_Neuropharmacol_30_843
PubMedID: 1664071

Title : Physostigmine (alone and together with adjunct) pretreatment against soman, sarin, tabun and VX intoxication - Harris_1991_Drug.Chem.Toxicol_14_265
Author(s) : Harris LW , Talbot BG , Lennox WJ , Anderson DR , Solana RP
Ref : Drug & Chemical Toxicology , 14 :265 , 1991
Abstract : Harris_1991_Drug.Chem.Toxicol_14_265
ESTHER : Harris_1991_Drug.Chem.Toxicol_14_265
PubMedSearch : Harris_1991_Drug.Chem.Toxicol_14_265
PubMedID: 1935706

Title : The influence of inhibitors and other factors on cholinesterases - Bajgar_1991_Sb.Ved.Pr.Lek.Fak.Karlovy.Univerzity.Hradci.Kralove_34_5
Author(s) : Bajgar J
Ref : Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove , 34 :5 , 1991
Abstract : Bajgar_1991_Sb.Ved.Pr.Lek.Fak.Karlovy.Univerzity.Hradci.Kralove_34_5
ESTHER : Bajgar_1991_Sb.Ved.Pr.Lek.Fak.Karlovy.Univerzity.Hradci.Kralove_34_5
PubMedSearch : Bajgar_1991_Sb.Ved.Pr.Lek.Fak.Karlovy.Univerzity.Hradci.Kralove_34_5
PubMedID: 1759111

Title : Detection of the organophosphorus nerve agent soman by an ELISA using monoclonal antibodies - Erhard_1990_Arch.Toxicol_64_580
Author(s) : Erhard MH , Kuhlmann R , Szinicz L , Losch U
Ref : Archives of Toxicology , 64 :580 , 1990
Abstract : Erhard_1990_Arch.Toxicol_64_580
ESTHER : Erhard_1990_Arch.Toxicol_64_580
PubMedSearch : Erhard_1990_Arch.Toxicol_64_580
PubMedID: 2073131

Title : A new H-oxime restores rat diaphragm contractility after esterase inhibition in vitro - Alberts_1990_Eur.J.Pharmacol_184_191
Author(s) : Alberts P
Ref : European Journal of Pharmacology , 184 :191 , 1990
Abstract : Alberts_1990_Eur.J.Pharmacol_184_191
ESTHER : Alberts_1990_Eur.J.Pharmacol_184_191
PubMedSearch : Alberts_1990_Eur.J.Pharmacol_184_191
PubMedID: 2209712

Title : Disposition and metabolism of two acetylcholinesterase reactivators, pyrimidoxime and HI6, in rats submitted to organophosphate poisoning - Garrigue_1990_Xenobiotica_20_699
Author(s) : Garrigue H , Maurizis JC , Nicolas C , Madelmont JC , Godeneche D , Hulot T , Morge X , Demerseman P , Sentenac-Roumanou H , Veyre A
Ref : Xenobiotica , 20 :699 , 1990
Abstract : Garrigue_1990_Xenobiotica_20_699
ESTHER : Garrigue_1990_Xenobiotica_20_699
PubMedSearch : Garrigue_1990_Xenobiotica_20_699
PubMedID: 2146816

Title : Neurotransmitter changes in guinea-pig brain regions following soman intoxication - Fosbraey_1990_J.Neurochem_54_72
Author(s) : Fosbraey P , Wetherell JR , French MC
Ref : Journal of Neurochemistry , 54 :72 , 1990
Abstract : Fosbraey_1990_J.Neurochem_54_72
ESTHER : Fosbraey_1990_J.Neurochem_54_72
PubMedSearch : Fosbraey_1990_J.Neurochem_54_72
PubMedID: 1967146

Title : A contribution to the mechanism of action of SAD-128 - Stalc_1990_Biochem.Pharmacol_40_2511
Author(s) : Stalc A , Sentjurc M
Ref : Biochemical Pharmacology , 40 :2511 , 1990
Abstract : Stalc_1990_Biochem.Pharmacol_40_2511
ESTHER : Stalc_1990_Biochem.Pharmacol_40_2511
PubMedSearch : Stalc_1990_Biochem.Pharmacol_40_2511
PubMedID: 2176500

Title : Putative M2 muscarinic receptors of rat heart have high affinity for organophosphorus anticholinesterases - Silveira_1990_Toxicol.Appl.Pharmacol_103_474
Author(s) : Silveira CL , Eldefrawi AT , Eldefrawi ME
Ref : Toxicol Appl Pharmacol , 103 :474 , 1990
Abstract : Silveira_1990_Toxicol.Appl.Pharmacol_103_474
ESTHER : Silveira_1990_Toxicol.Appl.Pharmacol_103_474
PubMedSearch : Silveira_1990_Toxicol.Appl.Pharmacol_103_474
PubMedID: 2339420

Title : A microassay-based procedure for measuring low levels of toxic organophosphorus compounds through acetylcholinesterase inhibition - Hammond_1989_Anal.Biochem_180_380
Author(s) : Hammond PS , Forster JS
Ref : Analytical Biochemistry , 180 :380 , 1989
Abstract : Hammond_1989_Anal.Biochem_180_380
ESTHER : Hammond_1989_Anal.Biochem_180_380
PubMedSearch : Hammond_1989_Anal.Biochem_180_380
PubMedID: 2817369

Title : Effects of soman and its antidotes on tracheal mucociliary transport of ferrets - Marin_1989_J.App.Physio_66_1390
Author(s) : Marin MG , Zwierzynski D , McBride RK , Culp DJ
Ref : Journal of Applied Physiology , 66 :1390 , 1989
Abstract : Marin_1989_J.App.Physio_66_1390
ESTHER : Marin_1989_J.App.Physio_66_1390
PubMedSearch : Marin_1989_J.App.Physio_66_1390
PubMedID: 2496095

Title : Comparison of the effects of diisopropylfluorophosphate, sarin, soman, and tabun on toxicity and brain acetylcholinesterase activity in mice - Tripathi_1989_J.Toxicol.Environ.Health_26_437
Author(s) : Tripathi HL , Dewey WL
Ref : J Toxicol Environ Health , 26 :437 , 1989
Abstract : Tripathi_1989_J.Toxicol.Environ.Health_26_437
ESTHER : Tripathi_1989_J.Toxicol.Environ.Health_26_437
PubMedSearch : Tripathi_1989_J.Toxicol.Environ.Health_26_437
PubMedID: 2709438

Title : Acute and sub-acute inhalation of an organophosphate induce alteration of cholinergic muscarinic receptors - Aas_1987_Biochem.Pharmacol_36_1261
Author(s) : Aas P , Veiteberg TA , Fonnum F
Ref : Biochemical Pharmacology , 36 :1261 , 1987
Abstract : Aas_1987_Biochem.Pharmacol_36_1261
ESTHER : Aas_1987_Biochem.Pharmacol_36_1261
PubMedSearch : Aas_1987_Biochem.Pharmacol_36_1261
PubMedID: 3593413

Title : Interaction of soman with beta-cyclodextrin - Desire_1986_Fundam.Appl.Toxicol_7_646
Author(s) : Desire B , Saint-Andre S
Ref : Fundamental & Applied Toxicology , 7 :646 , 1986
Abstract : Desire_1986_Fundam.Appl.Toxicol_7_646
ESTHER : Desire_1986_Fundam.Appl.Toxicol_7_646
PubMedSearch : Desire_1986_Fundam.Appl.Toxicol_7_646
PubMedID: 3803759

Title : Reactivation of Sarin- or Soman-phosphonylated human acetylcholinesterase by bis-pyridinium mono-oximes -
Author(s) : Sun MC , Li FZ , Chou TC
Ref : Biochemical Pharmacology , 35 :347 , 1986
PubMedID: 3942603

Title : Clonidine protection from soman and echothiophate toxicity in mice - Aronstam_1986_Life.Sci_39_2097
Author(s) : Aronstam RS , Smith MD , Buccafusco JJ
Ref : Life Sciences , 39 :2097 , 1986
Abstract : Aronstam_1986_Life.Sci_39_2097
ESTHER : Aronstam_1986_Life.Sci_39_2097
PubMedSearch : Aronstam_1986_Life.Sci_39_2097
PubMedID: 3784771

Title : Stereospecific reactivation of human brain and erythrocyte acetylcholinesterase inhibited by 1,2,2-trimethylpropyl methylphosphonofluoridate (soman) - De Jong_1985_Biochim.Biophys.Acta_830_345
Author(s) : De Jong LP , Kossen SP
Ref : Biochimica & Biophysica Acta , 830 :345 , 1985
Abstract : De Jong_1985_Biochim.Biophys.Acta_830_345
ESTHER : De Jong_1985_Biochim.Biophys.Acta_830_345
PubMedSearch : De Jong_1985_Biochim.Biophys.Acta_830_345
PubMedID: 4027255

Title : Influence of atropine upon ageing and reactivation of soman inhibited acetylcholinesterase from human erythrocytes. Preliminary communication - Kuhnen_1985_Arzneimittelforschung_35_1454
Author(s) : Kuhnen H , Schrichten A , Schoene K
Ref : Arzneimittelforschung , 35 :1454 , 1985
Abstract : Kuhnen_1985_Arzneimittelforschung_35_1454
ESTHER : Kuhnen_1985_Arzneimittelforschung_35_1454
PubMedSearch : Kuhnen_1985_Arzneimittelforschung_35_1454
PubMedID: 4084346

Title : Effects of HI-6 and pralidoxime on neuronal RNA in thalamic cholinergic sites - Martin_1985_J.Neurol.Sci_71_1
Author(s) : Martin LJ , Doebler JA , Anthony A
Ref : Journal of the Neurological Sciences , 71 :1 , 1985
Abstract : Martin_1985_J.Neurol.Sci_71_1
ESTHER : Martin_1985_J.Neurol.Sci_71_1
PubMedSearch : Martin_1985_J.Neurol.Sci_71_1
PubMedID: 2418157

Title : Neurobehavioral effects of repeated sublethal soman in primates - Gause_1985_Pharmacol.Biochem.Behav_23_1003
Author(s) : Gause EM , Hartmann RJ , Leal BZ , Geller I
Ref : Pharmacol Biochem Behav , 23 :1003 , 1985
Abstract : Gause_1985_Pharmacol.Biochem.Behav_23_1003
ESTHER : Gause_1985_Pharmacol.Biochem.Behav_23_1003
PubMedSearch : Gause_1985_Pharmacol.Biochem.Behav_23_1003
PubMedID: 4080770

Title : Treatment of poisoning by soman - Leadbeater_1985_Fundam.Appl.Toxicol_5_S225
Author(s) : Leadbeater L , Inns RH , Rylands JM
Ref : Fundamental & Applied Toxicology , 5 :S225 , 1985
Abstract : Leadbeater_1985_Fundam.Appl.Toxicol_5_S225
ESTHER : Leadbeater_1985_Fundam.Appl.Toxicol_5_S225
PubMedSearch : Leadbeater_1985_Fundam.Appl.Toxicol_5_S225
PubMedID: 4092890

Title : Studies on low dose sub-acute administration of soman, sarin and tabun in the rat - Dulaney_1985_Acta.Pharmacol.Toxicol.(Copenh)_57_234
Author(s) : Dulaney MD, Jr. , Hoskins B , Ho IK
Ref : Acta Pharmacologica et Toxicologica (Copenh) , 57 :234 , 1985
Abstract : Dulaney_1985_Acta.Pharmacol.Toxicol.(Copenh)_57_234
ESTHER : Dulaney_1985_Acta.Pharmacol.Toxicol.(Copenh)_57_234
PubMedSearch : Dulaney_1985_Acta.Pharmacol.Toxicol.(Copenh)_57_234
PubMedID: 4083033

Title : Isolation, anticholinesterase properties, and acute toxicity in mice of the four stereoisomers of the nerve agent soman - Benschop_1984_Toxicol.Appl.Pharmacol_72_61
Author(s) : Benschop HP , Konings CA , Van Genderen J , De Jong LP
Ref : Toxicology & Applied Pharmacology , 72 :61 , 1984
Abstract : Benschop_1984_Toxicol.Appl.Pharmacol_72_61
ESTHER : Benschop_1984_Toxicol.Appl.Pharmacol_72_61
PubMedSearch : Benschop_1984_Toxicol.Appl.Pharmacol_72_61
PubMedID: 6710485

Title : PAM-2 Cl, HI-6, and HGG-12 in soman and tabun poisoning - Boskovic_1984_Fundam.Appl.Toxicol_4_S106
Author(s) : Boskovic B , Kovacevic V , Jovanovic D
Ref : Fundamental & Applied Toxicology , 4 :S106 , 1984
Abstract : Boskovic_1984_Fundam.Appl.Toxicol_4_S106
ESTHER : Boskovic_1984_Fundam.Appl.Toxicol_4_S106
PubMedSearch : Boskovic_1984_Fundam.Appl.Toxicol_4_S106
PubMedID: 6724203

Title : Delayed neuropathy by the organophosphorus nerve agents soman and tabun - Willems_1984_Arch.Toxicol_55_76
Author(s) : Willems JL , Nicaise M , De Bisschop HC
Ref : Archives of Toxicology , 55 :76 , 1984
Abstract : Willems_1984_Arch.Toxicol_55_76
ESTHER : Willems_1984_Arch.Toxicol_55_76
PubMedSearch : Willems_1984_Arch.Toxicol_55_76
PubMedID: 6329137

Title : Brain neuronal RNA metabolism during acute soman toxication: effects of antidotal pretreatments - Doebler_1983_Neurochem.Res_8_997
Author(s) : Doebler JA , Bocan TM , Moore RA , Shih TM , Anthony A
Ref : Neurochemical Research , 8 :997 , 1983
Abstract : Doebler_1983_Neurochem.Res_8_997
ESTHER : Doebler_1983_Neurochem.Res_8_997
PubMedSearch : Doebler_1983_Neurochem.Res_8_997
PubMedID: 6194444

Title : Protection and induced reactivation of cholinesterase by HS-6 in rabbits exposed to soman -
Author(s) : Harris LW , Stitcher DL , Heyl WC
Ref : Life Sciences , 29 :1747 , 1981
PubMedID: 7300570

Title : Persistence of the anti-cholinesterase soman in rats\; antagonism with a non-toxic simulator of this organophosphate - Wolthuis_1981_Eur.J.Pharmacol_69_379
Author(s) : Wolthuis OL , Benschop HP , Berends F
Ref : European Journal of Pharmacology , 69 :379 , 1981
Abstract : Wolthuis_1981_Eur.J.Pharmacol_69_379
ESTHER : Wolthuis_1981_Eur.J.Pharmacol_69_379
PubMedSearch : Wolthuis_1981_Eur.J.Pharmacol_69_379
PubMedID: 7215436

Title : Reactivation of acetylcholinesterase inhibited by 1,2,2'-trimethylpropyl methylphosphonofluoridate (soman) with HI-6 and related oximes -
Author(s) : De Jong LP , Wolring GZ
Ref : Biochemical Pharmacology , 29 :2379 , 1980
PubMedID: 7426043

Title : Phosphorylation of acetylcholinesterase in bovine blood by Paraoxon and Soman - Nenner_1973_Arch.Toxikol_30_87
Author(s) : Nenner M
Ref : Arch Toxikol , 30 :87 , 1973
Abstract : Nenner_1973_Arch.Toxikol_30_87
ESTHER : Nenner_1973_Arch.Toxikol_30_87
PubMedSearch : Nenner_1973_Arch.Toxikol_30_87
PubMedID: 4685268

Title : Failure of toxogonin to reactivate soman-inhibited brain acetylcholinesterase in monkeys and regeneration of the enzyme -
Author(s) : Filbert MG , Fleisher JH , Lochner MA
Ref : Biochimica & Biophysica Acta , 284 :164 , 1972
PubMedID: 4627450

Title : Retarding effect of pyridinium salts on aging of soman-inhibited acetylcholinesterase -
Author(s) : Schoene K , Wulf R
Ref : Arzneimittelforschung , 22 , 1972
PubMedID: 4677079