Physostigmine-methiodide

General

Type : Derivative of physostigmine-eserine,Natural_modified,Carbamate,Indole

Chemical_Nomenclature : Pyrrolo(2,3-b)indolium, 1,2,3,3a,8,8a-hexahydro-1,1,3a,8(or 1,3a,8,8)-tetramethyl-5-(((methylamino)carbonyl)oxy)-, iodide, (3aS-cis)-

Canonical SMILES : CC12CCN(C1[N+](C3=C2C=C(C=C3)OC(=O)NC)(C)C)C.[I-]

InChI : InChI=1S\/C16H23N3O2.HI\/c1-16-8-9-18(3)14(16)19(4,5)13-7-6-11(10-12(13)16)21-15(20)17-2\;\/h6-7,10,14H,8-9H2,1-5H3\;1H\/t14-,16+\;\/m1.\/s1

InChIKey : SLSBBKOEHGUBBZ-XMZRARIVSA-N

Other name(s) : AR-45,6091-11-8


MW : 417.285

Formula : C16H24IN3O2

CAS_number :

PubChem : 111148

UniChem : SLSBBKOEHGUBBZ-XMZRARIVSA-N

IUPHAR :

Wikipedia :

Target

Families : Physostigmine-methiodide ligand of proteins in family: ACHE

Stucture :

Protein :

References (1)

Title : The reversible cholinesterase inhibitor physostigmine has channel-blocking and agonist effects on the acetylcholine receptor-ion channel complex - Shaw_1985_Mol.Pharmacol_28_527
Author(s) : Shaw KP , Aracava Y , Akaike A , Daly JW , Rickett DL , Albuquerque EX
Ref : Molecular Pharmacology , 28 :527 , 1985
Abstract : Shaw_1985_Mol.Pharmacol_28_527
ESTHER : Shaw_1985_Mol.Pharmacol_28_527
PubMedSearch : Shaw_1985_Mol.Pharmacol_28_527
PubMedID: 2417099