PIMP
sarin analogue. Less toxic but giving the same adduct
General
Type : Organophosphate,Surrogate OP,Nerve Agent G-series,Derivative of Sarin,Phthalimido,Isoindole
Chemical_Nomenclature : 2-[methyl(propan-2-yloxy)phosphoryl]oxyisoindole-1,3-dione
Canonical SMILES : CC(C)OP(=O)(C)ON1C(=O)C2=CC=CC=C2C1=O
InChI : InChI=1S\/C12H14NO5P\/c1-8(2)17-19(3,16)18-13-11(14)9-6-4-5-7-10(9)12(13)15\/h4-8H,1-3H3
InChIKey : KVQCPBJKHFOQSK-UHFFFAOYSA-N
Other name(s) : Phthalimidyl isopropyl methylphosphonate
MW : 283.22
Formula : C12H14NO5P
CAS_number :
PubChem : 87411366
UniChem : KVQCPBJKHFOQSK-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
References (4)
| Title : Comparison of inhibition kinetics of several organophosphates, including some nerve agent surrogates, using human erythrocyte and rat and mouse brain acetylcholinesterase - Coban_2016_Toxicol.Lett_248_39 |
| Author(s) : Coban A , Carr RL , Chambers HW , Willeford KO , Chambers JE |
| Ref : Toxicol Lett , 248 :39 , 2016 |
| Abstract : Coban_2016_Toxicol.Lett_248_39 |
| ESTHER : Coban_2016_Toxicol.Lett_248_39 |
| PubMedSearch : Coban_2016_Toxicol.Lett_248_39 |
| PubMedID: 26965078 |
| Title : Novel brain-penetrating oximes for reactivation of cholinesterase inhibited by sarin and VX surrogates - Chambers_2016_Ann.N.Y.Acad.Sci_1374_52 |
| Author(s) : Chambers JE , Meek EC , Chambers HW |
| Ref : Annals of the New York Academy of Sciences , 1374 :52 , 2016 |
| Abstract : Chambers_2016_Ann.N.Y.Acad.Sci_1374_52 |
| ESTHER : Chambers_2016_Ann.N.Y.Acad.Sci_1374_52 |
| PubMedSearch : Chambers_2016_Ann.N.Y.Acad.Sci_1374_52 |
| PubMedID: 27153507 |
| Title : Testing of novel brain-penetrating oxime reactivators of acetylcholinesterase inhibited by nerve agent surrogates - Chambers_2013_Chem.Biol.Interact_203_135 |
| Author(s) : Chambers JE , Chambers HW , Meek EC , Pringle RB |
| Ref : Chemico-Biological Interactions , 203 :135 , 2013 |
| Abstract : Chambers_2013_Chem.Biol.Interact_203_135 |
| ESTHER : Chambers_2013_Chem.Biol.Interact_203_135 |
| PubMedSearch : Chambers_2013_Chem.Biol.Interact_203_135 |
| PubMedID: 23123249 |
| Title : Synthesis and in vitro and in vivo inhibition potencies of highly relevant nerve agent surrogates - Meek_2012_Toxicol.Sci_126_525 |
| Author(s) : Meek EC , Chambers HW , Coban A , Funck KE , Pringle RB , Ross MK , Chambers JE |
| Ref : Toxicol Sci , 126 :525 , 2012 |
| Abstract : Meek_2012_Toxicol.Sci_126_525 |
| ESTHER : Meek_2012_Toxicol.Sci_126_525 |
| PubMedSearch : Meek_2012_Toxicol.Sci_126_525 |
| PubMedID: 22247004 |