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Inhibitor Report for: P9-benzothiadiazole

Fluorogenic Probe for Fast No-Wash Live Cell Imaging and Gel-Free Protein Quantification


General
Type Sulfur Compound, Fluorescent Probe, Thiadiazol, Sulfonyl
Chemical_Nomenclature 2-[[7-(dimethylamino)-2,1,3-benzothiadiazol-4-yl]sulfonyl-methylamino]-N-(6-hydroxyhexyl)acetamide
Canonical SMILES CN(C)C1=CC=C(C2=NSN=C12)S(=O)(=O)N(C)CC(=O)NCCCCCCO
InChI InChI=1S/C17H27N5O4S2/c1-21(2)13-8-9-14(17-16(13)19-27-20-17)28(25,26)22(3)12-15(24)18-10-6-4-5-7-11-23/h8-9,23H,4-7,10-12H2,1-3H3,(H,18,24)
InChIKey FAIBIJWJUPXKNF-UHFFFAOYSA-N
Other name(s) 8PM ; N~2~-{[7-(Dimethylamino)-2,1,3-Benzothiadiazol-4-Yl]sulfonyl}-N-Hexyl-N~2~-Methylglycinamide
________________________________________________________________________________________________
MW|429.55
Formula|C17H27N5O4S2
CAS_number|
PubChem|124220277
UniChem|FAIBIJWJUPXKNF-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | P9-benzothiadiazole ligand of proteins in family: Haloalkane_dehalogenase-HLD2
Stucture | 1 structure: 5UXZ: X-ray crystal structure of Halotag (Haloalkane dehalogenase) bound to the P9 benzothiadiazole fluorogenic ligand
Protein | rhoso-halo1

References:
Search PubMed for references concerning: P9-benzothiadiazole
    Title: The Cation-pi Interaction Enables a Halo-Tag Fluorogenic Probe for Fast No-Wash Live Cell Imaging and Gel-Free Protein Quantification
    Liu Y, Miao K, Dunham NP, Liu H, Fares M, Boal AK, Li X, Zhang X
    Ref: Biochemistry, 56:1585, 2017 : PubMed